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390. DMSO TRANSFORMS EYE TREATMENT – by Robert Yoho, MD

By November 11, 2025188 Comments
READER RESOURCES: THE APOCALYPSE ALMANAC: fun, treatments, and cures. FULLSCRIPT SUPPLEMENTS: top quality and economical.

Yoho Preamble

With respectful gratitude to AMD, I present the following summary. His DMSO work has improved my life in many ways, including helping with my ankle arthritis and macular degeneration. I am beginning to realize that DMSO rivals chlorine dioxide in medical importance. What follows is my synopsis of AMD’s post on DMSO and eye health; any errors or misinterpretations are mine.

HERE and HERE are my prior DMSO Substacks. The second is a 2500-word summary of AMD’s phenomenal book-length treatment of the subject, which was presented in about 10 novelette-length posts. This author might be the world’s leading authority on DMSO. He is now tabulating a great deal of data buried on the internet that might otherwise be lost.

You might also look at chapter 8 of The Apocalypse Almanac, which is linked at the top. It is a compendium of many natural cures, laced with my trademark humor.

This essay is about 5000 words. If you would rather read the 17,000-word original with all the footnotes and illustrations, HERE it is. AMD has an additional discussion about dosing behind a paywall that I have not included.

DMSO is a near panacea for eye treatment

Modern life assaults our eyes. Staring at screens all day, being indoors in unnatural light, never alternating focus between near and far—these habits accumulate damage over decades. Adding inflammatory diets, sedentary lifestyles, and chronic stress is a setup for eye disease. DMSO can counteract this damage and maintain our sight.

Eye diseases aren’t discrete entities—they’re interconnected symptoms arising from the same degenerative processes. Tired eyes, strain, dryness, floaters, and blurred vision all signal the same underlying problems: insufficient circulation, protein aggregation, inflammation, and fluid stagnation. These early warnings appear long before serious disease develops, providing opportunities to intervene before permanent damage occurs.

DMSO is a simple sulfur compound found in fruits and vegetables. The body tolerates massive doses—the lethal dose in animals is roughly equivalent to drinking a liter of DMSO—and even at concentrations 20 times higher than therapeutic doses, cells show no adverse effects. Between 80-90% of users report positive results with minimal side effects, including only temporary skin irritation and a characteristic odor.

DMSO entered medical research in 1961 after a chemist discovered that it could carry drugs through the skin. Within a few years, it became the most studied and most demanded drug in America. Researchers found it healed strokes, spinal injuries, chronic pain, and dozens of “incurable” conditions. Then, in 1965, the FDA banned all DMSO research based on questionable dog studies claiming it might damage vision, despite 37,000 human trial participants showing no eye problems. The ban lasted for decades, but DMSO remained available. Doctors who used it anyway discovered something remarkable: it didn’t harm the eyes. It healed them.

Today, hundreds of thousands have made their own DMSO eye drops and used them without incident. Patients report cataracts dissolving, floaters vanishing, macular degeneration reversing, and lifelong blindness lifting. One 75-year-old man, blind since birth, started seeing colors and details after using DMSO for sinus problems. A diabetic dog’s cataracts cleared. A woman who was legally blind from an eye injury healed in 24 hours. The improvements happen fast, often within days, and frequently work when nothing else can.

Why DMSO Heals Eyes

The eyes have enormous nutritional and energy demands. Blood flow restrictions that barely affect other organs can devastate vision. DMSO opens these channels, allowing nutrients already in the bloodstream to reach starving tissue. This explains why improvements often happen rapidly—the body already has what it needs, but circulation has failed.

The compound penetrates tissue rapidly and carries substances with it. Applied to the skin, it reaches the bloodstream within minutes. But the eyes concentrate DMSO beyond the amount that enters the blood. Studies show the cornea accumulates DMSO at 2-4 times the blood concentration. This means topical application delivers stronger doses to the eyes than oral or intravenous use—making 70% DMSO applied to closed eyelids often as effective as lower-concentration drops placed directly in the eye. These are harmless but create a burning sensation.

DMSO passes through the eye quickly, entering within minutes and exiting completely within hours. This rapid movement pulls excess fluid and waste out with it. The same mechanism that removes edema throughout the body also drains swollen corneas, clears clouded lenses, and eliminates protein debris that blocks vision.

Three properties make DMSO uniquely suited for the eyes. First, it stabilizes misfolded proteins in cataracts and macular degeneration, often restoring their normal function. Second, it increases blood flow to oxygen-starved retinal cells, rescuing dying tissue that conventional medicine considers permanently lost. Third, it reactivates dormant cells trapped in what researchers call the “cell danger response”—cells that have shut down but haven’t died, waiting for conditions to improve.

Safety Data

Extensive research confirms DMSO’s eye safety. Studies applying up to 100% DMSO directly to the eyes found no permanent damage. Rabbit eyes received 90% DMSO six times daily for two weeks—some showed temporary redness, but no lasting harm. Human trials with 108 patients used high-concentration DMSO for up to 19 months. Ophthalmologists examined every aspect of their eyes. No toxicity appeared. No cataracts formed. No vision changes occurred beyond improvements in the conditions being treated.

The threshold for DMSO damage is far above therapeutic doses. Clinical eye drops are available in 0.5-15% concentrations. Injecting 0.2% or less DMSO directly into rat eyes showed no functional impairment. Other common eye medications cause similar cellular changes at concentrations 10-1,000 times lower than DMSO.

One caveat exists with artificial lens implants. While low-dose DMSO drops (under 15%) appear safe with most modern implants, and no adverse events have been reported in the DMSO community, different lens materials have different DMSO resistance. High concentrations could, in theory, interact with certain plastics. German ophthalmologists who use DMSO recommend only low doses for anyone with implants.

Over 13 months of widespread DMSO use following published articles on the subject, only one FDA adverse event report appeared—someone was upset that their CBD contained DMSO. Among thousands using it, temporary stinging and odor remained the most common complaints. Seven people reported significant reactions, typically from mixing DMSO with something they were allergic to or using it with certain pharmaceuticals. The safety profile exceeds virtually every pharmaceutical and most natural remedies.

Surface Healing

The cornea and conjunctiva sit at the eye’s surface, directly exposed to DMSO drops. Multiple effects converge here. DMSO stimulates tear production by activating the parasympathetic nervous system. It reduces inflammation that blocks the tear ducts. It concentrates in the cornea at levels far exceeding the bloodstream. Combined, these actions make DMSO exceptional for the treatment of dry eyes.

Hundreds of users report the same pattern. Chronic dry eye that resisted prescription drops, warm compresses, and omega-3 supplements resolves within days of starting DMSO. One woman who required Meibomian gland probing—a painful procedure to unclog oil glands—no longer needs commercial eye drops after daily DMSO use. Another with brittle corneas and mast cell problems, forced to use drops several times daily because tears couldn’t cling to her damaged corneal surface, found her floaters dissolving and vision improving within two weeks.

Blepharitis—inflamed, crusty eyelids that often resist treatment for years—consistently responds to DMSO. In one study, all 17 patients with blepharitis improved after 4-6 weeks of DMSO combined with povidone-iodine. A 78-year-old man with rosacea and blepharitis who had failed a dozen treatments experienced remarkable improvement within hours. Multiple patients report eliminating eyelid inflammation, styes, and psoriasis around the eyes that had persisted for months or years.

DMSO can treat infections in the eye as well. Its antimicrobial properties work alone or enhance the activity of antibiotics and antivirals. Studies show it eliminates chronic bacterial and fungal infections on the cornea. In horses, DMSO plus itraconazole resolved chronic fungal infections in 80% of cases. In calves, DMSO with penicillin matched the efficacy of steroids for treating severe bacterial eye infections—without steroid risks.

Deeper inflammation responds too. Four cases of severe episcleritis that had failed steroids all improved with topical DMSO. Studies in dogs showed that DMSO reduces inflammation around the iris, decreases eye pressure, and prevents tissue damage. Human patients report the same. One doctor treated his own recurring iritis—inflammation that caused painful light sensitivity and required steroid drops—with 3% DMSO. The inflammation vanished in a week and hasn’t returned in two months.

Another user whose uveitis (inflammation of the pigmented layer of the eye, lying beneath the sclera and cornea) kept returning despite dexamethasone steroid eyedrops found that DMSO worked better, normalizing his eye pressure and saving his sight.

For viral infections, DMSO combined with antivirals treats shingles in the eye—a dangerous condition that can cause blindness. Two patients reported successfully treating ophthalmic shingles with DMSO, while published studies confirm it works when combined with antiviral drugs like 5-IDU.

Injuries around the eye heal rapidly. A 100-year-old woman fell, broke orbital bones, and developed nearly black bruises from blood thinners. DMSO cream applied daily turned the bruises from black to purple to yellow-green within three days. Burns, skin tags, and even psoriasis near the eyes respond. One firefighter suffered a chemical/heat burn from hot tar that troubled him for ten years—DMSO on the lower eyelids resolved it abruptly.

The most striking reports involve eyes scheduled for removal. One dog’s eye was scratched, became necrotic, and vets insisted it required urgent removal. The owners flushed the eye hourly with DMSO and colloidal silver. Within days, improvement was obvious. Six weeks later, the eye had healed entirely. Multiple similar stories exist—eyes dying, turning cloudy, losing all function, yet DMSO pulls them back from the edge. A Yorkie’s blind, dying eye regained sight after two weeks of DMSO and castor oil drops. A dog with an ulcerated eye scheduled for removal not only healed but regained vision in one month of DMSO treatment.

Clearing the Lens

Cataracts form when proteins in the eye lens misfold, lose solubility, and aggregate into cloudy deposits. DMSO stabilizes proteins and dissolves aggregates, making it naturally suited for cataracts. Multiple physicians report treating cataracts with DMSO. German ophthalmologists use it routinely. Success rates appear around 50%, though the types of cataracts that respond best remain unclear.

Patients report improvements ranging from subtle to dramatic. One man’s cataracts disappeared completely after four months of DMSO, saving him from surgery. A diabetic dog that went blind from cataracts regained sight as the cloudiness cleared. A woman whose January eye exam showed cataracts, early glaucoma, and peripheral vision loss returned in July with all measurements in normal ranges—her ophthalmologist told her to keep doing whatever she was doing.

The variation in results likely reflects differences in cataract composition. Some cataracts dissolve in DMSO, others don’t. Some require DMSO combined with other compounds. There is not enough data to determine which combinations work best for different cataract types. However, what’s clear is that for roughly half of users, DMSO provides an option to delay or avoid surgery.

Several approaches exist. Some use DMSO eye drops alone at concentrations from 3-15%. Others combine DMSO with vitamin C, tea tree oil, and coconut oil (which also treats Demodex infections that worsen cataracts), or N-acetylcarnosine drops. One person who used DMSO with coconut oil and tea tree oil to kill Demodex mites and dissolve cataracts reported improved vision.

Steroid eye drops increase cataract risk by 245-311%, with 15% of users developing them. They also increase glaucoma risk by 41%. This makes DMSO’s anti-inflammatory effects particularly valuable, as it reduces inflammation without the risks that come with long-term steroid use.

One study in diabetic rats showed DMSO significantly slowed cataract formation. While more research is needed, the existing evidence, combined with hundreds of user reports, suggests DMSO can both treat existing cataracts and prevent new ones from forming.

Dissolving Floaters

Floaters appear when proteins aggregate in the vitreous humor—the gel-like substance filling the eye behind the lens. Floaters respond exceptionally well to DMSO, with higher success rates than cataracts. Dozens of users report floaters vanishing, often within days or weeks of starting treatment.

The mechanism likely involves DMSO’s protein-stabilizing effects combined with its ability to improve fluid circulation through the vitreous. Free-floating protein aggregates are more accessible to DMSO than deposits locked within the lens. As DMSO enters and exits the eye, it dissolves the proteins and carries them out in the draining fluid.

Reports are consistent across users. One person with vitreous detachment symptoms started DMSO and noticed fewer floaters and flashes within a week, giving clearer vision. Another simply stated, “My eye floaters are gone.” A woman in a cataract trial saw her floaters completely vanish before any cataract changes appeared. Multiple people report the same pattern—floaters that had persisted for months or years disappear within days of starting DMSO drops.

Remarkably, applying DMSO outside the eye often eliminates floaters as well. Several people found that applying DMSO to the neck or temples cleared floaters without directly putting anything in the eyes. This suggests DMSO concentrates in the vitreous portion of the eye even when applied elsewhere on the body, though the concentration from drops remains higher.

The vitreous changes with age, shifting from a gel to a liquid state around age 45. This shrinkage makes vitreous detachments more common and can worsen floaters. DMSO appears to stabilize the gel structure, potentially explaining why it not only clears existing floaters but may prevent age-related vitreous problems. At low concentrations, DMSO stabilizes gels; at high concentrations, it destabilizes them. Therapeutic doses fall well within the stabilizing range.

Restoring Vision

The most extraordinary reports involve blindness reversing—sight returning after years or decades of darkness. A 75-year-old man who has been blind in one eye since birth started using DMSO topically and as a nasal spray for sinus problems. After two months, he noticed colors and detail where previously only light and shadow existed. Eight months later, he could walk around his house using the formerly blind eye, safely navigating doors and furniture. He estimates 15-20% of vision has been restored and continues to improve slowly.

Similar cases appear throughout the medical literature. One man, blind for 30 years after dynamite exploded in his face, began seeing light flashes after applying DMSO to his head. Another lost sight in both eyes after being hit by a car while skating. High-dose DMSO drops restored vision in the completely blind eye and improved the partially functional one. A man who was nearly blind for years, dependent on others to cut his food and clean his house, regained independent function after a year of DMSO.

These cases likely reflect DMSO’s ability to rescue dormant retinal cells. Studies show DMSO protects retinas from toxic light damage, prevents radiation-induced cataracts, and shields tissue from ischemia—insufficient blood flow. Multiple studies in animals engineered to develop retinal degeneration found that low-dose DMSO prevented retinal thinning and preserved visual function.

In one study, diabetic rats received DMSO injections. Their retinal function improved significantly, with enhanced electrical responsiveness and increased retinal thickness compared to controls. Mouse studies found similar results across multiple research teams—DMSO prevents retinal cells from dying when exposed to damaging stimuli.

The mechanism appears to involve multiple factors. DMSO reduces oxidative stress, which damages retinal cells in macular degeneration. It increases circulation to oxygen-starved tissue. It reactivates cells trapped in a dormant state between functional and dead. Most importantly, it reaches these cells in concentrations high enough to work when applied topically—something oral supplements often fail to achieve due to poor circulation to diseased retinal tissue.

Macular Degeneration

Macular degeneration occurs when waste products from retinal cells accumulate behind the retina. Normally, a layer of cells called the retinal pigment epithelium clears this debris daily. When this system fails, waste builds up, killing retinal cells and destroying central vision. Conventional medicine offers little beyond injections that slow progression in some patients.

DMSO attacks multiple causes simultaneously. It removes protein aggregates that form the waste deposits. It increases circulation, bringing nutrients to weakened cells. It reduces inflammation. It may even enhance the enzyme activity that breaks down debris. Most importantly, it reaches the retina in concentrations high enough to work.

Reports of DMSO reversing macular degeneration appear frequently. One 90-year-old man, unable to read due to macular degeneration, received daily DMSO drops plus oral DMSO. After one month, he resumed reading books. Another person’s vision improved from 25/40 to 20/25. His ophthalmologist attributed it to his monthly eye shots suddenly working after 4 months, though the patient knew DMSO was responsible. (Yes, ophthalmologists stick needles into your eyes if you have macular degeneration, and yes, it is painful.)

A university retina doctor told one patient their retinal scarring had decreased 50% after they started DMSO. Another tested their vision with an Amsler chart that showed distorted lines due to macular degeneration, then used DMSO drops twice daily for three months. The distortions vanished.

A patient with severe central vision loss and hallucinations from advanced macular degeneration (the “wet” kind) used 40% DMSO eyedrops for three weeks. The ink blotch hallucinations disappeared, central vision cleared, and they could drive at night without glasses.

Multiple people report that DMSO prevented their macular degeneration from progressing and stabilized their vision after years of decline. A patient who used DMSO drops for 6-7 years said it effectively stopped the disease. Another started DMSO when his central vision was severely compromised and peripheral vision damaged, then found that after several months, his vision improved enough to pass driving tests.

The improvements extend beyond age-related macular degeneration. One person had a branched retinal vein occlusion, which obstructs blood flow to part of the retina. He saw four years of improvement plateau after two years of traditional injections, but adding oral DMSO and eye drops last October caused a slow but definite improvement. He has hope that the injections will no longer be necessary.

DMSO also treats macular edema (swelling), macular holes, and macular puckers. It prevents new blood vessels from forming in wet macular degeneration, which is the severe form. It is driven by vascular endothelial growth factor (VEGF), which costly injectable drugs attempt to suppress. Studies show DMSO inhibits VEGF and blocks abnormal blood vessel formation in corneal cells and cancer cells. Multiple users report success with both wet and dry macular degeneration.

The key limitation is circulation. If blood flow to the eyes remains severely restricted, nutrients can’t reach their targets even with DMSO’s help. This explains why some patients respond better than others—DMSO dramatically improves existing circulation but can’t overcome complete blockages. Combining DMSO with circulation-enhancing approaches like specialized acupuncture or addressing underlying vascular disease provides the best results.

Retinitis Pigmentosa and Retinal Protection

Retinitis pigmentosa is a genetic disorder that causes gradual vision loss, typically starting in the periphery. Rod cells in the eyes fail to secrete a substance that prevents cone cells from dying. The condition affects 1 in 4,000 people and is considered incurable except for one rare subtype where an $850,000 gene therapy works about half the time.

DMSO treats retinitis pigmentosa. An early 1973 study found improvements, leading to a larger 1975 trial with 50 patients. Of these, 22 had improved visual acuity, 9 had improved visual fields, 5 had improved night vision, only 2 continued to worsen, and the rest saw no change. This was evidence that DMSO stopped the degenerative process.

One patient who could barely see hand motion in his right eye and had 20/200 vision in his left eye started DMSO. Five days later, left eye vision improved to 20/70, and he could count fingers at 5 feet with the right eye. Three months later, his left eye reached 20/50. When he tried stopping DMSO for a week, his vision immediately worsened. Restarting treatment restored it. Two years after beginning treatment, his vision remained stable at 20/50.

Animal studies confirm DMSO’s protective effects. Mice engineered to develop retinitis pigmentosa received 0.01% DMSO in their drinking water—an extremely low dose. Their retinas didn’t thin like those of the untreated mice. In another mouse study, DMSO increased retinal electrical responsiveness by 56-107% compared to normal mice, while untreated retinitis pigmentosa mice showed 8-42% decreases.

Studies also show DMSO prevents retinal damage from bright light, radiation, toxins, and insufficient blood flow. In mice, DMSO fully protected retinal cells from toxic bright light that killed most cells in untreated animals. Another study found 92-93% loss of retinal function after light exposure in untreated mice, but only 30-33% loss in DMSO-treated mice. A patient who damaged their eyes from excessive sunlight exposure healed them with DMSO. Another who accidentally stared at the sun too long also recovered with DMSO treatment.

DMSO protects the lens from oxidative damage, prevents X-ray-induced cataracts when applied before exposure, and enhances recovery from eye surgeries. One person who got IV DMSO after an optic nerve stroke believes it saved their eyesight. Another with a retinal bleed experienced partial vision loss episodes that cleared minutes after applying DMSO gel to the affected eyelid—the “greyouts” likely reflected insufficient blood flow, which DMSO immediately corrected.

Multiple patients report that DMSO helps with retinitis pigmentosa. One with the condition uses drops that help his visual field. Reports from the broader DMSO community echo these improvements.

Glaucoma Treatment

Glaucoma damages the optic nerve, causing characteristic peripheral vision loss. Elevated eye pressure often accompanies this damage, leading conventional medicine to equate glaucoma with high pressure. Every mainstream therapy focuses on lowering pressure, yet this approach fails to address other factors damaging the optic nerve. DMSO works differently—it not only reduces pressure but also directly protects the nerve.

DMSO excels at removing edema and obstructions to fluid drainage. Studies in rabbits found it effectively and progressively lowered eye pressure over time. Another rabbit study showed a DMSO-brinzolamide gel designed for glaucoma treatment reduced pressure without toxicity. DMSO also lowers intracranial pressure—which somewhat elevates eye pressure—without reducing blood flow to the brain, making it invaluable for traumatic brain injuries.

Patients report dramatic improvements. One person whose vision in one eye had reduced to a blur from glaucoma started DMSO. Two months later, they could see specific letters and numbers for the first time in two years. The burning sensation from the drops lasted only 15 seconds. It was nothing compared to the orbital bone pain from four different glaucoma drops used multiple times daily, not to mention two surgeries.

Another man had severe glaucoma with elevated pressure despite painful drops prescribed by his ophthalmologist. After one month of DMSO cream and a PEMF device, his pressure normalized without medication. His doctor noted that his visual acuity improved by two lines on the vision chart. When he stopped using DMSO, glaucoma progressed to painful corneal sloughing. Reapplying DMSO reduced the pain to manageable levels. Adding 1ml oral DMSO daily provided further improvement.

A practitioner who treated world leaders applied DMSO daily for his own glaucoma. Over the course of one month, his vision improved significantly. Multiple other reports describe glaucoma pressure normalizing, pain rapidly resolving, and medications no longer being needed. This was presumably because DMSO addressed the congestion or drainage obstruction causing elevated pressure.

Eight patients confirm similar results. One person states, “DMSO works better than dexamethasone for uveitis. It saved my sight and normalised my eye pressure.” The consistency across reports, combined with studies showing DMSO’s drainage-enhancing effects, strongly suggests it treats glaucoma effectively—addressing both pressure elevation and nerve protection simultaneously.

Vision Correction

The most unexpected benefit is that DMSO can correct nearsightedness. Multiple people report that their vision has improved so much that they no longer need glasses or contacts. Given DMSO’s history with alleged vision problems, some were concerned until they realized their prescription had become too strong, not their eyes too weak.

A man reported that his vision became blurry after applying DMSO to his legs. An eye exam revealed improvement of 0.5 diopters in the left eye and 0.25 in the right. He needed a new contact prescription because his vision had improved—something that had never happened in years of worsening eyesight. Another person’s astigmatism improved, allowing them to wear a milder glasses prescription than they’d worn in decades. Someone with presbyopia (age-related reading difficulty) found it disappearing. Another man with the same situation no longer needs glasses to read texts.

A 60-year-old who had always been nearsighted and was beginning to need bifocals found that they couldn’t see clearly through reading glasses while taking 30ml oral DMSO daily. Taking the glasses off revealed they could read the smallest print clearly. Their nearsightedness didn’t worsen, no cataracts formed, and at age 60, they can read tiny print without glasses.

A 43-year-old man’s eyesight had deteriorated steadily, progressing to bifocals. After starting selenium supplementation and applying DMSO to an ingrown toenail three times daily, his eyes healed dramatically within two weeks. He no longer needs glasses except for very close work. Another person used DMSO cream on their jawline nightly, noticed better eyesight the next day, continued with weekly PEMF, and eliminated glasses after 25 years of wearing them. He no longer needs them for reading or driving.

The pattern is clear: DMSO specifically corrects nearsightedness but doesn’t cause farsightedness. The same observation appears many times among people using DMSO in Germany. This suggests that DMSO addresses pathologic processes that cause the eye to become longer and narrower, leading to nearsightedness.

Three mechanisms explain this. First, DMSO reduces excess fluid swelling in the eye, which pushes it forward. Studies show it reduces corneal edema. Second, DMSO relaxes the ciliary muscle, which, when chronically contracted, causes nearsightedness. Third, chronic nearsightedness stretches the back of the eye, causing the sclera to thin and remodel with disorganized collagen. The tissue loses elasticity and becomes nearly impossible to revert to normal. DMSO excels at loosening and normalizing tissue in this state. One study found DMSO decreased fibrin production in chronically inflamed eyes—another factor contributing to the restoration of a normal eye shape.

This correction addresses modern life’s assault on our eyes. Fluid stagnation from sedentary lifestyles causes buildup in the eyes. Constant screen staring locks eyes into chronic nearsightedness. An unhealthy momentum builds, making it harder each year for the eyes to return to normal focusing. Standard medicine prescribes glasses that lock in the narrow, lengthened state rather than correcting the underlying issue before it becomes permanent.

DMSO provides an easy way to address these problems at their root. It reduces fluid buildup, relaxes chronically contracted muscles, and softens remodeled tissue—allowing the eye to return to its natural shape. Combined with eye exercises, the effects amplify, as DMSO’s muscle-relaxing properties help loosen overstrained or hardened eye muscles, thereby enhancing the effectiveness of the exercises.

General Vision Enhancement

Beyond treating specific diseases, DMSO improves overall vision quality. AMD has more than 25 people who commented on his posts, all of whom reported improved eyesight with DMSO use. The improvements vary. Some are subtle, others dramatic, but the pattern is consistent. Eyes feel refreshed. Vision becomes crisper. Colors appear more vibrant. Night vision improves. Eye strain from screens decreases.

One person dabbed DMSO on their eyelids and immediately improved their pool game. He suddenly saw shots clearly. Another got dramatic vision improvement just from applying DMSO above their ankle. Eight people report less blurriness. Eleven reported reduced eye dryness. Three reported reduced eye strain, particularly from screens. Multiple reports describe eyes feeling refreshed after DMSO use.

The improvements extend to preventing problems before they start. German doctors increasingly view low-dose DMSO drops as preventive eye care for healthy eyes, particularly given the modern demands of screen time. Users report maintaining eye freshness, improving tear quality, reducing night glare, and preventing problems from developing. Positive effects often appear after the first few applications.

One practitioner who routinely uses DMSO reports applying it to his own eyes when he feels tired, noting immediate and rapid improvement. A Los Angeles doctor found that several patients could read fine print more easily after only one week of applying DMSO to their eyes. When people experience blurred vision from device use, a single drop in each eye provides relief.

The mechanism likely involves multiple factors. DMSO removes subtle protein aggregates clouding the cornea, lens, or vitreous. It reduces inflammation that impairs eye function. It increases circulation, bringing nutrients to hungry tissue. It reactivates dormant cells operating below capacity. Most importantly, it does all this simultaneously, addressing the interconnected degenerative processes underlying age-related vision decline.

Eye diseases aren’t discrete entities—they’re interconnected symptoms arising from the same degenerative processes. Tired eyes, strain, dryness, floaters, and blurred vision all signal the same underlying problems: insufficient circulation, protein aggregation, inflammation, and fluid stagnation. These early warnings appear long before serious disease develops, providing opportunities to intervene before permanent damage occurs.

Conclusion

DMSO transforms ophthalmology by addressing root causes rather than managing symptoms. It doesn’t just slow vision loss—it restores lost sight. It doesn’t mask inflammation—it eliminates it. It doesn’t temporarily reduce pressure—it corrects drainage obstruction. This explains why it treats dozens of seemingly different eye conditions; they all stem from the same degenerative processes.

The evidence is overwhelming. Hundreds of thousands have used it safely. Patients who have been blind for decades regain sight. Cataracts dissolve. Floaters vanish. Macular degeneration reverses. Infections clear. Injuries heal. Nearsightedness corrects. The improvements occur quickly —often within days —and succeed even when conventional medicine has exhausted its options.

Three factors make DMSO uniquely effective. First, it concentrates in the eyes at levels far exceeding those achieved with oral or intravenous administration. Corneal concentrations reach 2-4 times the blood levels. Second, it penetrates tissues rapidly, reaching areas that medications typically can’t access. Third, it addresses multiple disease mechanisms simultaneously rather than targeting single pathways.

The simplest applications often work best. Many people apply 70% DMSO to closed eyelids rather than putting drops directly in the eyes, finding this approach as effective as lower-concentration drops but with little stinging. Others use diluted drops at concentrations ranging from 0.5% to 15%. Some combine DMSO with specific nutrients or medications targeting particular conditions. (Yoho comment: Castor oil, for example, works for cataracts.) The flexibility allows customization to individual needs and tolerance.

Safety concerns that blocked DMSO research for decades proved baseless. The original 1965 dog studies used doses never approached in humans and produced effects that never appeared in 37,000 trial participants. This led to the FDA research ban. Subsequent research found no eye toxicity at any reasonable concentration. Modern usage confirms this—hundreds of thousands of applications without serious adverse events.

The tragedy is not only that DMSO was suppressed, which harmed millions. The greater tragedy is that conventional medicine still has no answer for most eye diseases. Macular degeneration, retinitis pigmentosa, many retinal diseases, chronic floaters, and progressive vision loss are considered incurable. Cataracts require surgery. Glaucoma demands lifelong medication or procedures. Yet a simple compound that costs pennies, requires no prescription, and heals conditions ophthalmologists consider impossible to reverse is almost unknown.

This pattern repeats throughout medicine. Effective, inexpensive, off-patent therapies get buried while expensive interventions become standard—not because they work better, but because they’re profitable. The DMSO story reveals how this happens: regulatory agencies claim to protect public safety while actually protecting pharmaceutical profits. Decades of denial create institutional momentum impossible to overcome with mere evidence.

We’re entering an era in which trusting the medical system for healthcare is no longer possible. Fortunately, tools like DMSO, which are hidden in plain sight, enable direct control over our health.

Eye health reflects overall health. The same inflammatory and circulatory disorders that cause chronic illness first appear in the eyes, providing early warning signs. Diabetes, smoking, and autoimmune conditions are all strongly linked to specific eye diseases. These illnesses often become evident in the eyes before showing elsewhere, giving us opportunities to address underlying problems before heart attacks occur and unhealthy patterns become permanent.

Modern life assaults our eyes. Staring at screens all day, being indoors in unnatural light, never alternating focus between near and far—these habits accumulate damage over decades. Adding inflammatory diets, sedentary lifestyles, and chronic stress is a setup for eye disease. DMSO can counteract this damage and maintain our sight.

Yoho postscript: Where to get DMSO, the tools for handling it, and how to take it orally.

DMSOStore.com on Amazon HERE is reasonably priced and convenient. Always be sure that what you are buying is 99.995 % pure. I keep a gallon around at all times. The ceramic measuring spoons HERE are optimal; if you use low-quality plastic ones, you will taste it. Avoid metal ones, as they dissolve a little as well. Be careful; ceramics break when dropped. Always mix DMSO in a glass and use only purified water to dilute it.

To take DMSO orally, start with a teaspoon in a glass of water daily. Depending on the condition, increase up to a tablespoon in a glass of water three times a day. One study showed no complications when a cup of pure DMSO was consumed daily for several months.

Editing credits: Elizabeth Cronin and Jim Arnold of Liar’s World Substack.

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188 Comments

  • Avatar DistantSun says:

    Are there any guidelines with respect to the concentration of DMSO for use in eyes? Do you know any physicians who consult virtually with patients? Many thanks! (I have had myopia/astigmatism since 2nd grade, and I also have floaters and the beginnings of cataracts.)

  • Avatar A Midwestern Doctor says:

    Based on all the reports I’ve received, I am somewhat convinced DMSO should be the standard of care for floaters as no good option exists and there seems to be a very high response rate to DMSO. A colleague decided to test it after I told him (as a prospective trial) and in 10 days his were largely gone.

    • Avatar Otis says:

      Thank you for your detailed DMSO series. They turned on the light so a medical revolution is happening. They saved me and helped many I shared information with.
      Thanks to Dr. Yoho for this concise summary. Great impact for sharing.

    • Avatar helen.tomlin says:

      My husbandu2019s floater disappeared after two sessions of red light therapy

    • Hello AMD, it’s X @PMDrake158 25/40 to 20/25. I’ve increased my dosage from 1x to 2x DMSO eye drops a day. I now do not use my glasses indoors for most of the day especially morning. Just when I read and in the evening. Last visit to the University showed NO progression in my macular degeneration. I’ve added red light/NIR therapy to my protocol per information from Dr. Jack Kruse.
      Thank you for all your help (substack writings) and thank you Dr. Yoho for your writings.

      • Avatar Denise says:

        What kind or brand of DMSO eye drops do you use or did you make them? What potency please.

        • Amandha Vollmer’s dmso.store sells two potencies, 20% and 40% labeled “‘strong'”. Dr. Jacobson research at the University of Oregon found that for macular degeneration the stronger dosage was much more effective. Before I read Amandha Vollmer’s book I made a 50/50 blend of DMSO and distilled water and rubbed it on my eyelids, around my eyes and above my eyebrows twice a day.
          I also take a tsp a day if I’m not leaving the house for 2 days, DMSO body odor from oral dosages. The DMSO body odor only comes from oral dosing.

          • Avatar THOMAS E MOORE JR says:

            I’m concerned about the effect on liver & kidney’s over time. Especially if a person has a preexisting issue w/ one or both. Like cirrhosis. Primarily when taken orally. AI says it’s life threatening. Even at 1/4 tsp/20drops.

          • Avatar Robert Yoho, MD says:

            The massive literature suggests otherwise. AI is frequently GIGO

          • Avatar Rebecca says:

            Which AI do you use? Most of the AI programs wcontracted with Pfizer for medical information, so consider the root source!

          • Avatar Randy says:

            Caution! u201Cdmso.storeu201D is NOT u201Cdmsostore.comu201D; dmso.store is a u201CHealth Freedom Private Clubu201D of which you must become a u201Cmemberu201D before you can buy anything. Most experts, including A Midwestern Doctor, Dr Yoho, and myself recommend the 99.995% pure product from dmsostore.com.

          • Avatar yantra says:

            thank you. i also use dmsostore brand.

        • Avatar Robert Yoho, MD says:

          70 percent small amount on eyelids twice daily dmsostore.com

      • Avatar Lisa Nash says:

        Do you put the drops in your eyes? I saw your other comment where you put it around your eyes. Can you clarify?

        • Yes, I put the eye drops in my eyes or the corner and let it roll in. The around my eyes comment was if you can’t get the eye drops, then make a 50/50 blend and rub it around your eyes, forehead, temple which is what I did before buying eye drops from Amandha Vollmer’s dmso.store. The bottles and roll-ons I buy from dmsostore.com.

        • Avatar Robert Yoho, MD says:

          dmso in eyes is harmless even at 99.995 percent but it stings. I used it like that for a month but finally couldn’t stand it

    • Avatar Maria says:

      How does one find a doctor skilled in DMSO? And should you trust DMSO sold on Amazon?

      • Avatar Robert Yoho, MD says:

        private message me and I will give you options. I am not in practice however

        • Avatar Maria says:

          Thank you for replying. Iu2019ll get right to the issue. I have a man in my church who lives alone, and has gone blind I think from u201CRetinitis Pigmentosau201D. Would love to find someone who could work with him even to possibly restore seeing shapes etc., Any help would be much appreciated!

      • Avatar Robert Yoho, MD says:

        only criteria for good DMSO is 99.995 percent pure

  • Avatar FREED0ML0VER says:

    I’ve been using DMSO with CDS for a dental infection, and I’ve noticed that my night vision is improving.

  • Avatar Lina says:

    Better be working for my eyes b/c I am going for itu2026uD83DuDE02 against my husbandu2019s pleading.

  • Avatar Don says:

    Got rid of my floaters too by simply taking DMSO and Chlorine Dioxide orally, for another purpose. Wasn’t even thinking about floaters at the time.

  • Avatar BFP says:

    Wish Iu2019d seen (no pun intended) this article 4 months ago before my cataract surgery! Still not doing well but will start on eyelids tonight. Have a dead spot in middle of right eye, and have slight blockage slightly to the left – poses an issue with oncoming traffic when driving.

  • Avatar LiMaxiB says:

    Want to write more but as itu2019s late eyes are struggling. Thank you. uD83DuDE4FuD83CuDFFBuD83DuDC95uD83CuDF37

  • Avatar EK MtnTime says:

    If only I didnu2019t reek of garlicu2026would MSM work for the eyes?

  • Avatar Craig says:

    Even though my wife has successfully used castor oil drops in her eyes for ten years for cataracts, floaters and dry eyes she has started using DMSO on her eyelids. I am going to start using it too after reading about people that had their need for reading glasses stop. It will be interesting to see what happens. Thanks for all the information and reporting that it works well when applied to eyelids.

    • Avatar Donna Ruth says:

      Hope you would not mind answering a few questions.
      How much DMSO does she use in a dropper?
      Does she mix it with water?
      What concentration? 30/70?
      How many times a day?
      Every day?
      How long before seeing a change with cataracts?
      Thanks!

      • Avatar George says:

        I started using 20% DMSO and 4.5% N-Acetylcarnosine with Glycerin eye drops (Opticlear from ebay) daily for about a month. I have a cataract covering one of my eye reducing my vision to 20/50 with corrective lens. I have a 40% DMSO solution and it stings a lot.
        20% not so much. I will try a higher concentration DMSO on the eye lid and see if I like it better
        Otherwise, will increase to 30% DMSO. I use 1 drop of the Opticlear solution followed by 1 drop of the DMSO solution. daily. This follows a procedure I found as a letter to the editor in a peer review publication that I downloaded. https://pdfs.semanticscholar.org/2b44/d9d226a935461818c3f75c52b29ce7c67ac9.pdf
        I am open to changing this by increasing to 2X per day or higher DMSO solutions.

        20 drops = 1 mL (approx.) I have confirmed this using an analytical balance with accuracy to 0.0001 g. (close enough for what we are doing)
        1 g (H20) = 1 mL = 1 cc (cubic cm)

        I purchase a PhysiciansCare Eye Wash Solution, Sterile Isotonic Buffered Solution for these dilutions because it is sterile. Based on my experience in preparing microorganism solutions for laboratory use, it is very easy to contaminate anything.

        I do my dilutions in my kitchen. I prep my work area with cleaner such as a home prepared vinegar solution and wipe with a clean paper towel I follow this up with a wipe down of 80 proof cheap vodka using another clean paper towel. I use a graduated cylinder to my dilutions if using a volume/volume dilution.

        For example: make a 100mL 10% DSMO solution.

        Pour 10 mL of DSMO into grad cylinder up to the 10 mL mark then fill to 100 mL with the buffered solution. You now have a 10% volume to volume dilution or a 10% DSMO solution. You may want to purchase a couple of sized of grad cylinders. say 100 and 250 mL but only use glass.

        Storage: I purchase boston round amber bottles for storage and dropper bottles.
        I usually purchase a box at a time. But smaller quantities are available from Amazon.

        I never pour direct from the concentrated DMSO bottle but pour an estimated amount into a 250 mL graduated Erlenmeyer flask (Amazon).
        Never return anything remaining DMSO from the flash back to the original DMSO bottle to prevent contamination. Any remaining DMSO in the flask goes down the drain.

        All storage bottles should be sanitized by boiling in water and use tong to remove the bottles from the hot water. I also rinse the storage bottles with 190 proof Everclear. It does not take much. Let them dry completely before adding solutions to them. Pour out excess Everclear into the sink.

        My protocol for percent solutions may change soon but the basic lab prep will also remain strong.

        Be blessed.

        • Avatar Donna Ruth says:

          Wow, thanks for the detailed response!

          • Avatar George says:

            It all simple algebra from high school and high school chemistry. Ratio and proportions.
            My excessive prep before doing anything is from my Jr College microlab.
            I was the laboratory tech student that made all the agar plots for microscopic examination. It is easy to contaminate or cross-contaminate.
            I do not like rubbing alcohol or methanol so I use ethanol. Best place to go is the liquor store. 190 proof is the highest percentage that you can get without using a co-solvent with makes it undrinkable/poisonous. Alcohol will always contain water.

            Laboratory glassware just makes it easier with fewer mistakes.

            I also make serial dilutions. For example if I want to make a 20% solution,
            I will make a stock 40 or 60% solution and dilute from there to get the desired concentration. That way I do not require a clean space often.
            I do not want to interfere with more important things like my wife grinding wheat, making bread, and most important preparing delicious meals for me.

        • Avatar Robert Yoho, MD says:

          twice to three x a day

  • Avatar Marie says:

    I have Sju00F6grenu2019s syndrome and my eyes were very dry and inflamed, despite using eyedrops After reading MWDu2019s post on DMSO for eye conditions I made eyedrops using 70% colloidal silver and 30% DMSO (99.9%). Iu2019ve been using it for about three weeks with great results Stings when first applied but the relief is instantaneous and I donu2019t need eyedrops any more.

  • Avatar JohnnyBGood says:

    How do you use it for floaters? Do you drop into your eyes like red eye medicine? Won’t it burn your eyes?

  • Avatar yantra says:

    Thanks for this great condensed version – and also that you provide it in your resonant, easy-listening voice, which is instrumental for those of us who don’t want to have our eyes glued to a screen. I am hoping that a friend who is basically going blind from a cataract and absolutely does not want to get his eyes cut with standard cataract surgery will be willing to give it a listen.

  • Avatar Paul_ says:

    Does DMSO improve Stargarts Syndrome?
    Is there a way to avoid the smell?

  • Avatar mejbcart says:

    THIS IS PRICELESS ROBERT! THANK YOU!!!!

  • Avatar Dee says:

    The Midwestern Doctor is kind of cool that way. 🙂

  • Avatar Cris Hamilton says:

    I need a recipe please

  • Avatar Kat Sullivan says:

    I’ve been using canine eye drops – DMSO and colloidal silver – for a few months and my cataracts are disappearing, and my night vision has greatly improved. They only sting a little and my eyes feel good after. I don’t frequent eye doctors (or any other doctors). I enjoy these articles as much as a good short story. BTW reading glasses are ridiculously cheap on Amazon but now I’m looking forward to ditching them.

  • Avatar Citizen_Jimserac says:

    This is a topic of wide public interest and so we thank both Drs. for posting on this matter which affects many of us.
    As with cancer “treatments”, a vast industry has grown up around eye treatments, surgery, lasers. Much of it is good but it is my belief, as was the case with chemotherapy, that the surgery benefits, for example for cataracts, have been overemphasized as the first treatment of choice and its success exaggerated or qualified by clinical results and problems afterwards. Meanwhile, I researched Cineraria Maratima and found a good deal of contradictory, confusing information, though some appear to have used it with success.
    DMSO is starting to appear promising to me with little or no confirmation from the eye industry just as there is little or no comment from the cancer industry about people recovering from Stage 4 cancers using Ivermectin combined with the non-FDA approved drug Fenbendazole. It would seem that the eye journals, at least the official ones, have cleverly introduced standards routinely rejecting such articles or else examining the issue under impossible or unrealistic test conditions. All information about DMSO has been effectively suppressed for decades by actions of the FDA which demonized it long ago and we are just now starting to learn of the extraordinary and potential therapeutic benefits in a wide variety of situations. Remaining completely unknown outside of a few rare books are the light therapy techniques although new researching is starting to emerge. This stuff is completely outside my field so I’m stumbling through it just like everyone else.

  • Avatar DLREPP says:

    I have followed and read what AMD has written but I need to find somewhere or someone who can direct me to the specifics of using for the many eye conditions listed. Please direct me!

    • Amandha Vollmer’s DMSO book #1 on Amazon. I get my eye drops 40% DMSO from her dmso.store from Canada. You can’t get DMSO eye drops in the US yet.
      Her book is the best written for eye drops.

      • Avatar Denise says:

        Can I ask how you that this is her store..I know she has another called yumnaturals..

        • She has three stores. dmso.store for all her DMSO products. Yumnaturals for food and makeup items and one other for education seminars.

          • I recommend reading her book because she went over all DR. Jacobson research at the University of Oregon who made DMSO famous. She gives lots of dosages for many ailments.

          • I use dmsostore.com in the USA for bottles and roll-ons.

          • Avatar Randy says:

            If youu2019re going to keep promoting your supplier, Iu2019m going to keep warning people that your supplier is not the source A Midwestern Doctor and Dr Yoho recommend.

            u201Cdmso.storeu201D is NOT u201Cdmsostore.comu201D; dmso.store is a u201CHealth Freedom Private Clubu201D of which you must become a u201Cmemberu201D before you can buy anything. Most experts, including A Midwestern Doctor and Dr Yoho, recommend the 99.995% pure product from dmsostore.com.

            P.S. Trump has imposed a tariff on goods coming from Canada, where dmso.store is located. dmsostore.com is based in Florida.

          • Avatar Robert Yoho, MD says:

            please do not post repetitive messages
            best

          • Avatar Randy says:

            If youu2019re going to keep promoting your supplier, Iu2019m going to keep warning people that your supplier is not the source A Midwestern Doctor and Dr Yoho recommend.

            u201Cdmso.storeu201D is NOT u201Cdmsostore.comu201D; dmso.store is a u201CHealth Freedom Private Clubu201D of which you must become a u201Cmemberu201D before you can buy anything. Most experts, including A Midwestern Doctor and Dr Yoho, recommend the 99.995% pure product from dmsostore.com.

            P.S. Trump has imposed a tariff on goods coming from Canada, where dmso.store is located. dmsostore.com is based in Florida.

      • Avatar Randy says:

        If youu2019re going to keep promoting your supplier, Iu2019m going to keep warning people that your supplier is not the source A Midwestern Doctor and Dr Yoho recommend.
        u201Cdmso.storeu201D is NOT u201Cdmsostore.comu201D; dmso.store is a u201CHealth Freedom Private Clubu201D of which you must become a u201Cmemberu201D before you can buy anything. Most experts, including A Midwestern Doctor and Dr Yoho, recommend the 99.995% pure product from dmsostore.com.
        P.S. Trump has imposed a tariff on goods coming from Canada, where dmso.store is located. dmsostore.com is based in Florida.

  • Avatar linda collins says:

    Such valuable information! But what about people who have already had cataract surgery? Can those people be benefited by DMSO?

    • Avatar Robert Yoho, MD says:

      yes

      • Avatar Ruth says:

        Iu2019ve had bilateral cataract surgery with lens implants 7 years ago but am told developing a u201Csecondary cataractu201D that will require YAG procedure-laser. If I want to try DMSO first, would I just use a solution on eye lids or around eyes. Since we are told not to use drops in our eyes if implants but yet DMSO gets into cells when used topically, would it be safe in my case? If so, how much and where?

      • Avatar linda collins says:

        Thank you for replying. I’m supposing (due to your inclusion of Ruth’s question) that I could put it around eyes or eye lids? If this is correct, please say “yes” or elaborate.

      • Avatar Deb.Butler says:

        Not so sure, because when cataracts are removed they replace the lens with a plastic lens, and DMSO does not interact well with plastic. In fact, they are finding that contact lenses are shedding nano particles of plastic into the eye.

        • Avatar Ruth says:

          Iu2019m confused because you replied applying around my eyes would be best bet, but then because of the lens implants, DMSO does not interact well with plastic. Do you mean only if DMSO would have u201Cdirect u201C contact with implanted lenses?

          • Avatar Deb.Butler says:

            Yes, I put it directly into my eyes, but I have not had cataract surgery. When my husband was diagnosed with macular degeneration I spent 8 hours researching DMSO and the eyes. I also take DMSO internally. It will take anything it comes in contact with, with it. I apply magnesium gel to my legs, and then apply DMSO over it. The DMSO will absorb the magnesium through all seven layers of skin and into the muscles, then bloodstream, then blood cells. Does that answer your question?

          • Avatar Ruth says:

            Thank you.

  • Avatar Marilyn F says:

    Listening to you read this article made it enjoyable. Your voice is clear, confident & soothing.
    Thank you!

    • Avatar Robert Yoho, MD says:

      I smoked like an idiot for ten years and it gave me a smoky baritone ha

      • Avatar Susan Middleton says:

        Thank you for sharing this info with people

        I have been a fan of DMSO for around 40 years but pretty much had to figure out things myself as literature was very scant back then

        I think the smell is what held back its popularity for alot of people

        It was hard to use it and then go to work bc the smell is not really noticeable to the person using it

        I cannot thank you enough for your efforts and hope to afford a paid subscription someday

        God bless you!

  • Avatar Marilyn F says:

    We really need a little book that recommends dosing, listing the concentration & means for internal & topical application. How do we dilute 100% DMSO, with saline, filtered water?
    This is such an exciting time in healthcare. Thank you.

    • Avatar Jeannie Kaasa says:

      Yes that would be very helpful. Sometimes dmso causes skin irritation and Iu2019d hesitate to put it directly in my eyes

    • Avatar Robert Yoho, MD says:

      filtered water

    • AMD gives dosing in his writings, however I recommend Amandha Vollmer’s book #1 on Amazon for DMSO eye drops, and I buy my DMSO 40% eye drops from her dmso.store from Canada because you can’t sell DMSO eye drops in the US yet (RFK JR is working on it). Otherwise I would just make a 50/50 blend with distilled or RO water and rub it on my eye lids and around my eyes like I used to do before reading Amandha Vollmer’s book.

      • Avatar Marilyn F says:

        Great. Thanks for the info. I use full strength DMSO on my neck & shoulder. My skin becomes pretty irritated, so I apply cortisone after it dries. The irritation made me leery of putting it around my eye. Now Iu2019m motivated to try it.

        I printed out most of AMD writing on DMSO. So much info!!! Donu2019t you love him?
        Lies Are Unbecoming does a really good synopsis on AMD – an abbreviated version, but really good. Itu2019s a nice review & reminds of things I missed in his articles.
        We are all learning this together so we can bypass the medical industry. A rainbow of knowledge came out of the COVID/VAX debacle. u263AuFE0F

      • Avatar Randy says:

        If youu2019re going to keep promoting your supplier, Iu2019m going to keep warning people that your supplier is not the source A Midwestern Doctor and Dr Yoho recommend.

        u201Cdmso.storeu201D is NOT u201Cdmsostore.comu201D; dmso.store is a u201CHealth Freedom Private Clubu201D of which you must become a u201Cmemberu201D before you can buy anything. Most experts, including A Midwestern Doctor and Dr Yoho, recommend the 99.995% pure product from dmsostore.com.

        P.S. Trump has imposed a tariff on goods coming from Canada, where dmso.store is located. dmsostore.com is based in Florida.

        • Avatar Marilyn F says:

          Donu2019t you like how they copy almost the exact wording of dmsostore.com? I always remember it because itu2019s very bright green. Good stuff.
          I like the dmso roller balls. They donu2019t have the awful odor of the solution. However, I dilute the solution for my cat.

    • Avatar Denise says:

      The book , healing with DMSO is pretty good

    • Avatar Sandra Koukal says:

      Get the book, many suggestions of use, with recipes.

    • Avatar Rebecca says:

      I put a video together showing how I mix and use DMSO. I also show how it is mixed for my neighbor Dan to nebulize. He is curing his COPD with DMSO. https://youtu.be/6LXwDj6DJj4

  • Avatar Michelle says:

    I forwarded this to my sister who is dealing with diabetic neuropathy and a detached retina. So happy to hear the great results being achieved by combining DMSO with other treatments! Thank you!

  • Avatar Dr Linda says:

    I have wondered about DMSO for eye issues. I appreciate the dosage info. I am upping my game today.

    I have noticed my night vision shifts to accommodate darkness very quickly, within a second or two.

  • Avatar Jeannon Kralj says:

    Thank you, Dr. Yoho. I really appreciate comprehensive coverage like this.

    First heard about DMSO on late 1960s TV documentary, but even then it had the hint of being an “outlaw” miracle cure.

    I am beginning to wonder if the treatment is worse than the cure for my incurable autoimmune eye condition. I am addicted to steroid eye drops and those eye drops are leveling continuous injuries to my eyes.

    I remember clearly when my autoimmune eye condition presented. It was a year 2000 beautiful spring day and I was walking out to my car in my driveway and I was “shot” in my left eye with burning and stinging sensation. I got myself to the nearest ophthalmologist and the next day my right eye “broke through.”

    Don’t think I could benefit much from DMSO for my eye condition. I might be able to space out the daily times taking of the eye drops, but waiting for signs of a flare-up has its own contraindications.

    C R A P !

    Chronic Retinal Autoimmune Pusillanimosity

  • Avatar Jeannie Kaasa says:

    Great summary and yes please send more; sometimes the full studies are too much for me to wade through

  • Avatar KC & the Sunshine says:

    My daughteru2019s dog kept getting ugly, cauliflower looking growths on one of her eyelids. They were the size of a large
    peanut or small cashew, and drooped from her upper lid, onto her field of vision. Her vet kept u201Cslash & burningu201D them off, repeatedly. Theyu2019d return within weeks.
    I put DMSO gel on them 3-4x and BOOM, gone, never to return! Itu2019s been well over a year!

  • Avatar SteveBC says:

    Hey, Doc. In 2015 when I was diagnosed with an early cataract in my right eye and seeds in my left eye, I used drops of C60 in coconut oil. They were gone in 4-6 months. For anyone who tries DMSO on their cataracts and finds no progress, I recommend trying C60 on its own or mixed with DMSO. I suspect that different cataracts will react to different substances. I use the C60 sold by shopc60.com. High quality source.

    • Avatar Robert Yoho, MD says:

      Steve this is a great case report. Here is an AI search for the readers. I make no comment about this:

      The Molecule
      C60 is a spherical molecule made of 60 carbon atoms arranged like a soccer ball, also called buckminsterfullerene Healthline. It was Healthline discovered in 1985 and won a Nobel Prize in Chemistry in 1996. It’s being marketed as a powerful antioxidant supplement, typically dissolved in olive oil or other carrier oils Healthline.
      The Hype: That Famous Rat Study
      A 2012 study by Baati et al. claimed that rats given C60 in olive oil nearly doubled their lifespanu2014from 22-26 months to 42 months PubMed. This sparked massive interest in C60 supplements.
      But there were problems: The study used only a small number of rats (6 per group), and critics noted the control group had unusually short lifespans, while the C60 group lived far longer than typical rats in any other longevity research Fight Aging!. Some questioned whether the study inadvertently measured intermittent fasting benefits, since rats were fasted overnight before C60 administration Fight Aging!.
      The Reality Check: Failed Replication
      A 2020 study attempted to replicate the results in mice and found no significant lifespan extension from C60 in olive oil compared to controls PubMed. Worse, they discovered that C60 in olive oil exposed to ambient light levels became toxic, causing significant illness and death in mice within two weeks PubMed.
      The Safety Problems
      Solvent Contamination: Many commercial C60 products contain residual toxic solvents like toluene from the manufacturing process, which can accumulate in the body and damage the central nervous system PapiliotherapeuticsPapilio Therapeutics. Purple-colored C60 oil indicates solvent contaminationu2014pure C60 in oil should be a clear reddish-orange color Papiliotherapeutics.
      Quality Control Chaos: The FDA doesn’t regulate C60 supplements, and one study testing products from various online vendors found marked differences in purity, concentration, and appearance between brands Healthline. There are no regulatory standards or purity criteria for C60 supplements Atlasofscience.
      Purity Requirements: C60 should be at least 99.9% pure to avoid residual solvents, soot, or other toxic fullerenes SES Research Inc.. High-purity C60 powder should be black and metallic-looking; brownish powder indicates lower purity Atlasofscience.
      The Research Status
      Most C60 research has been in cells or animals, with only a handful of human studiesu2014primarily on skin care applications Healthline. There’s no good scientific evidence to support most supplement claims WebMD.
      Bottom Line
      C60 supplements represent everything problematic about the unregulated supplement industry: dramatic claims based on questionable animal studies that couldn’t be replicated, zero human trials, no FDA oversight, widespread quality control issues, and potential toxicity concerns. The 2012 rat study that launched this market has serious methodological questions, and the 2020 replication failureu2014plus discovery of light-induced toxicityu2014should give anyone pause.
      If someone insists on trying C60 despite these red flags, they’d need to verify: 99.99% purity, sublimation purification (no solvents), third-party testing, proper storage away from light, and transparent manufacturing. Even then, they’re essentially conducting an uncontrolled self-experiment with an unstudied molecule.

      • Avatar SteveBC says:

        ShopC60 uses only 99.9..% sublimated C60 molecules. Kenneth Swartz is the main guy there, and the website has very extensive information about how they do what they do and about C60 itself. I don’t know where you got this negative information, but I suggest you call Ken and ask him as well as go on his site and review the information there. I think he calls it C60 Academy or something like that.
        Without question, my experience has been extremely positive. Not only did it eliminate my cataract and seeds within a few months (and they have not returned), my biological age began dropping in relation to my chronological age in a way I cannot attribute to anything else. My chronological age is 74, but my measured biological age is 60-62. I have asked about 10 people over the past several years how old they thought I was (when I knew they did not know my chronological age), and every single one says I am 60, and their mouths literally drop open when they hear I am 74. I do have a substantial supplement program, but I have some reason to believe that a good portion of that difference is due to the C60.
        I have not experienced any negative effects ever. I work with an energy healer who always sees the C60 as highly positive energy for me whenever we test it, noticeably more so than any other supplement I take.
        I use the coconut oil version, dosed according to their guidelines.

        • Avatar yantra says:

          very interesting. your experience makes me wonder if this is another case where the mainstream ptb (pubmed, healthline, webmd et al) are doing standard turf-protection, just like with dmso and Clo2, etc.

      • Avatar Mac says:

        Do you connect it to Putin giving Trump a soccer ball for Barron? I literally question everything. Idk. Symbols are everything, even in chemistry. Iu2019ll look into this

    • Avatar Robert Yoho, MD says:

      castor oil is also reported efficacious

      • Avatar SteveBC says:

        Yes, I’ve heard that but have not had to use it, so have no experience with it in that application.

      • Avatar Shanti Love says:

        Correct, from direct experienceu2026and nature’s botox uD83DuDE05 but I’m using aloe vera juice as well, direct from the plant into the eyes via rubbing the eyelids and lashes with my eyes closed looselyu2026it goes in.

  • Avatar Denise says:

    Hi, will DMSO help with the type of cataract that you get from retinal surgery? If so, what form and what potency please.

  • Avatar JMi1949 says:

    Dr Yoho, I am a recent subscriber and appreciate the information you are providing. It is difficult to find information on the topics you discuss. Thanks so much for your work. I have an 82 year old friend who suffers from a severe case of shingles. I have suggested he try DMSO along with 5-iodo-2′- deoxyuridine (IDU). It seems to be effective for shingles treatment, although my friend has had a terrible painful experience for several years with shingles that will not go away. It is located on his right chest and rib cage area. Do you have any other articles or suggestions to offer for his condition? His Dr looked at the article I gave him and dismissed it. He has been treated with traditional drugs and basically told there is nothing else that can be done for his condition. Thanks again for your excellent work. Jim Ivy

  • Avatar Diane Hart says:

    Thank you so much, Dr Yoho! I am greatly appreciative of the work you did to create a summary of AMD’s fabulous work! I have a hard time getting through the long articles produced by AMD, even though they are incredible. I never get more than halfway throughu2026 I am so grateful that you have created a Summary so that I can have access to this amazing information.
    I am now going to start DMSO on my eyelids and temples to try to address my dry eyes and numerous floaters. I also had vitreous detachment so hopefully this treatment will improve my eyes overall. Thanks again!

  • Avatar Sandra Street says:

    thank you so much for this information. it is so hard to find good information and then there are those that promise for $ that has no real improvement.

  • Avatar THOMAS E MOORE JR says:

    I’m concerned about the effect on liver & kidney’s over time. Especially if a person has a preexisting issue w/ one or both. Like cirrhosis. Primarily when taken orally. AI says it’s life threatening. Even at 1/4 tsp/20drops.

    • Avatar Robert Yoho, MD says:

      massive literature suggests it is safe
      study on 60 people who drank a cup of full strength for 3 months: no issues

      • Avatar THOMAS E MOORE JR says:

        Fighting survival odds of 80% 1yr 60% for 2yrs w/ albumin just got up to 2.8. dimethyl sulfone u2014 hepatotoxic in cirrhosis (Toxicol Lett 2019)
        Inhibits platelet function u2014 platelets already 89
        Just drained 4.5 L ascites
        If you could at least direct me to studies, would be appreciated 😉

  • Avatar Michele Anderson says:

    Where can DMSO be purchased premixed or where can reliable safe directions to make this be found? Thank you!

  • Avatar Randy says:

    u201Cuse only purified water to dilute it.u201D Purified water (distilled or RO) is fine for topical or oral consumption, but for mucus membranes, like the eyes and nose, a saline solution is better. This is what I use: Sterile Saline Solution, 0.9% – USP Grade – 0.05u03BCm Filtered and Sterile – Made in USA – Four Pack: 4x500mL Bottles (2000mL Total) https://a.co/d/a0MGmLE

  • Avatar Deb.Butler says:

    My husband was diagnosed with MD at his last eye exam. I have been diagnosed with glaucoma (a medical term for high pressure in the eye, which is common in people who have MTHFR genetic SNPs) and cataracts. I am not doing the treatments for either that eye doctors try to force on you. My husband and I are both putting drops of 30% DMSO and 70% black Jamaican castor oil in each eye twice a day as recommended by Dr William Makis. Here is where you can find it

    https://barecatbody.com/

    A Midwestern Doctoru2019s Substack, The Forgotten Side of Medicine, has a lengthy article about DMSO and the eyes also

  • Avatar Nama Paula says:

    I read all 17,000 of AMDu2019s article earlier. Yours is more user friendly to share with my non medical friends. THANKS!
    ??? Would Fiji water qualify as u201Cpurified wateru201D in your opinion???u2764uFE0FuD83DuDE4F

  • Avatar VN says:

    Where do we order good quality eye drops and oil or cream and what is the concentration and frequency for eye treatment??

  • Avatar Rochelle Porto says:

    Great info – whatu2019s the best place to get DMSO ?

  • Avatar Plutarch says:

    DMSO is a byproduct of the paper mill industry. Poisonous chemicals are used to strip pine bark from pine trees. The toxic byproduct is sold for health supplementation.

    DMSO may provide limited nutritional benefits to cells simply because pine bark is highly medicinal. However, it also has well-documented toxic side effects from the chemicals used by the paper mills that we should not ignore.

    DMSO increases ROS production, decreases cell viability, and induces mitochondrial dysfunction through impairing glutamate transporter synthesis.Overuse causes traumatic brain injury, epilepsy, and neurodegeneration.

    The screenshot below is from a study entitled https://pmc.ncbi.nlm.nih.gov/articles/PMC4169574/.

    As you can see, DMSO is a neurotoxin. https://pmc.ncbi.nlm.nih.gov/articles/PMC9337627/ or substances that interfere with normal function and/or compromise adaptation in the central and/or peripheral nervous system. https://pubmed.ncbi.nlm.nih.gov/28121745/ various central nervous system side effects, such as epileptic seizures, stroke, transient global amnesia, and more. Studies have shown that https://pmc.ncbi.nlm.nih.gov/articles/PMC2682536/. If somebody is poisoned with COVID-19 technology or shedding, DMSO is a wrong and potentially dangerous treatment.

  • Avatar Shanti Love says:

    Thank you uD83DuDE0A uD83DuDE4FuD83CuDFFC Immensely grateful uD83DuDE4FuD83CuDFFC

  • Avatar yantra says:

    Thank you Robert for reading this wonderful synopsis of MWD’s article to us. here is my experience with DMSO eye application: i took a tiny shot glass of isotonic fluid and added 1 drop of pure dmso (creating what was probably a one-half percent solution). i began to do this daily, bathing my eyes for a few seconds several times per day. it feels so refreshing!

    i have no serious eye problems, but being on the computer irritates them.

    two weeks later i was hand-sewing for awhile. in recent years, threading a tiny needle has become increasingly challenging for me. but i noticed NO PROBLEM threading even a tiny filament part of a thread thru a very tiny needle slot. it was like when i was 7 years old! Last time i sewed a few months ago it was quite difficult; i had even resorted to needle-threaders at times.

    with this encouragement, i bumped up to 2 drops in the solution, then 5 drops, which may be a 2% DMSO solution. i am using it daily, often 5 to 10 times daily for a few seconds, especially if on the computer much. it feels great. thank you very much for helping to spread the word on this miraculous healer of the eyes. i have sent your podcast on to friends who are suffering with cataracts, etc. one has already noticed “discernible” improvement in her vision.

  • Avatar Kerrylee says:

    You have the best voice for narration. Like DMSO on the skin, I think I absorb more when I hear your drops. A relative has terrible macular degeneration and is in need of this information. Unfortunately, she is so tied into a “prestigious” university’s medical system (one also in trouble for its transgender surgeries on children) that she isn’t open to any of this information.

    I remember the wise crack that grandparents and grandchildren have the common enemy of the parents. Considering the elderly are all in on bureaucratic poisonous medicine, as are the young, I see the truth in the statement. I feel like we are the Dr. Seuss characters in Whoville screaming to be heard.

  • Avatar Donna says:

    Thank you for the summary, and yes, I would like more summaries.
    There was mention in your summary of people who fixed a problem, cataracts only mentioned, I think, but when they stopped using the drops, their eyes deteriorated so had to start the drops again. I’m curious if you know if using the drops forever is required generally. Do you know of conditions that get fixed and dmso applications are no longer needed?

  • Avatar Teri B says:

    Where do you purchase DMSO? Could any dr prescribe it??

  • Avatar THOMAS E MOORE JR says:

    I used Grok. Knowing it has a general bias, I went back & pushed the issue. As usual it was able then to think outside the box & came up w/ a protocol of people who were dying used w/ % of stabilization rate. This AI at least MANY times has shown it can access info but does not provide as a primary response, whether medical or political, a nonconforming view. I wish there were more doctors like Mr. Yoho. I now have a soon in-law w/extreme high blood pressure testicle cancer tumor removed but BP is not lowering even w/ doubled meds. W/ protocol this 38yr old will be dead in 1-2 yrs leaving my daughter who is legal blind from juvenile macular degeneration alone. So over all we are on our own & the med profession is more dangerous than helpful for us average people for the wisdom of the few doctors is not accessible.

  • Avatar rob says:

    Thank you for this substack, your dedication and commitment. I will start to use DMSO topically on my eyelids as I have glaucoma in my left eye and significant floaters in both eyes.

  • Avatar Nicholas says:

    I am currently 69 years old, and my vision has been deteriorating since I was 24. My prescription was +6 for near and +5 for far last year. It abruptly improved to +5 and +4, respectively, after a month of using DMSO for a non-eye condition. The only explanation that springs to mind is DMSO.

  • Avatar Katherine Tidman, Ph.D. says:

    Fascinating?

  • Avatar Katherine Tidman, Ph.D. says:

    Surviving healthcare is a very good title. I have both progressive MS and ADHD and only non-medicines have helped me

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