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460. Osteoporosis: How Pharma Invented a Fake Diagnosis, Sold Poison Drugs, and Hid the Real Cures

By July 22, 2026July 23rd, 2026106 Comments
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In the last eighteen months, Charlotte has fractured her ribs, broken her wrist, and experienced a spontaneous vertebral collapse. She is otherwise healthy and eats well, and her parents lived nearly to a hundred. If she breaks her hip, the data indicate she has roughly a one-in-three to one-in-two chance of being dead within a year, and I am afraid that is what is coming.

Her doctors have given her the soft label “osteopenia,” a phony statistical category I will dismantle below. Charlotte does not have osteopenia. Charlotte has osteoporosis. Three fragility fractures in a year are the disease announcing itself in plain language. I wrote this for her so she has the information to reverse what she can and to refuse what she should.

Why bone disease deserves your attention more than breast cancer

About one in five Americans over age 65 fractures a hip. Depending on the cohort, between a quarter and more than half of those people are dead within a year. Many survivors never walk normally again and end their days in nursing homes. As a public health problem, this dwarfs breast cancer, yet cultural attention is reversed. Hip fractures happen mostly to women, but men are not exempt; men who break a hip die at higher rates than women.

The orthodox approach is to scan everyone, label about half of postmenopausal women with a manufactured precondition called “osteopenia,” and feed them oral or injected bone drugs that, in the populations they are mostly given to, do not prevent the fractures that matter and cause new fractures of their own. The story of how this came to be is representative of how modern healthcare works.

The osteopenia con: a hotel meeting in Rome

In June 1992, the World Health Organization convened a small group of bone experts at a hotel near the top of the Spanish Steps in Rome. Until that meeting, osteoporosis had no numerical definition; doctors mostly diagnosed it after a bone fracture. The funders wanted a number because it could be screened for, and a screening test could be sold alongside a drug. Merck, the maker of Fosamax (alendronate), had funded the development of inexpensive dual-energy X-ray absorptiometry (DEXA) scanners and was pushing hard to get them into doctors’ offices.

Anna Tosteson of Dartmouth, who was in the room, later told NPR what happened. After two or three days of arguing, the group settled on −2.5 standard deviations below the mean for a healthy young adult as the osteoporosis cutoff. Anyone with a T-score of −1.0 to −2.5 was given a new label coined on the spot: osteopenia. Tosteson said the term was created mostly because public health researchers prefer clean categories. None of them imagined it would be marketed back to patients as a disease that needed treatment. Steven Cummings of UCSF, one of the most cited osteoporosis researchers alive, said flatly that there was “no basis, no biological, social, economic or treatment basis, no basis whatsoever” for using −1.0 as a clinical line, and that, as a consequence, “more than half of the population is told arbitrarily that they have a condition they need to worry about.” Alix Spiegel told this story for NPR in a piece you can read here.

So roughly half of postmenopausal women now wear a label that was invented off the cuff in a hotel suite during a meeting paid for by a company that needed more women on its drug. The chairman of that meeting, John Kanis, has confirmed in print that osteopenia was never meant to be a disease. It became one because Merck and the DEXA-scanner industry needed it to be one. Once the label existed, the algorithm wrote itself: scan, label, prescribe, repeat.

Bisphosphonates: poison sold as medicine

Fosamax, Boniva (ibandronate), Actonel (risedronate), and the IV drug Reclast (zoledronate) are bisphosphonates, sold as bone-saving drugs. For the women they are mostly prescribed to, they are worse than nothing. TheNNT.com summarizes the Cochrane data with their usual clarity: in postmenopausal women without a prior fracture, no high-quality study has shown a meaningful reduction in fractures that matter. The drugs show a fracture benefit only in the smaller subset of women who already have osteoporosis on a scan and a previous broken bone. That is a population perhaps a tenth the size of the population being medicated.

These drugs do real damage. The Fosamax label and the post-marketing literature now document:

Atypical femoral fractures. The thigh bone snaps with almost no force. The drugs were sold to prevent this and instead cause it. The risk rises with treatment duration beyond about three to five years.

Osteonecrosis of the jaw. The jawbone deteriorates, sometimes after routine dental work. Merck has paid out hundreds of millions of dollars to settle these claims; in one Fosamax settlement, the company paid $28 million to dispose of about twelve hundred suits.

Esophageal erosion and esophageal cancer. Oral bisphosphonates are sufficiently corrosive that patients are advised to remain upright for thirty minutes after dosing. Some users still develop esophageal injury, and the cancer signal has been debated for years.

Atrial fibrillation. Multiple analyses link bisphosphonate use to higher rates of this dangerous arrhythmia.

Bone and muscle pain, GI distress, eye inflammation, kidney injury, low calcium, hypersensitivity reactions. Lists of forty-plus reported side effects are not hard to find.

There are roughly eighty million bisphosphonate prescriptions written in this country. The financial reason is simple. Doctors who administer IV versions in their offices keep a margin on what they buy and inject; the same arrangement applies to Lupron for prostate cancer and several oncology drugs. If a physician set up that kind of revenue split with another physician, it would be illegal fee-splitting. Routed through a corporation, it is the business model. I covered the same dynamic in the oncology section of Butchered by “Healthcare”.

Comment: If your doctor wants to put you or your spouse on a bisphosphonate and there has been no prior fragility fracture, you should walk out. If there has been a prior fracture, the conversation is more complicated, but it should still begin with the question, “What are we going to do about her hormones, vitamin D, vitamin K, magnesium, and muscle mass first?”

The newer drugs are worse

When the bisphosphonate franchise started showing wear, pharma rolled out three replacements. Each is more dangerous than the drug it was meant to improve upon.

Prolia (denosumab) is a twice-yearly injection that powerfully suppresses bone resorption while it is on board. The catch is that it does not remain in the bone the way a bisphosphonate does. When a dose is missed or the patient stops, bone turnover rebounds above pretreatment levels, and a wave of multiple spontaneous vertebral fractures can occur. The FDA Prolia label reports that six percent of women who stopped Prolia in the pivotal trial developed new vertebral fractures, and three percent developed multiple new vertebral fractures. The Cleveland Clinic and others now describe roughly one in fourteen patients who discontinue without sequential antiresorptive coverage as suffering rebound fractures, and registry data link discontinuation to increased mortality. Once on Prolia, a patient is effectively trapped on it, because getting off it safely requires giving another antiresorptive (often a bisphosphonate) for an extended period to mop up the rebound. Patients are rarely told this when they are signed up.

Evenity (romosozumab) is a monthly injection given for one year. It carries a black box warning for heart attack, stroke, and cardiovascular death. It is contraindicated in anyone who has had a heart attack or stroke in the prior year. The FDA prescribing information exists because the pivotal ARCH trial showed an excess of major cardiovascular events with Evenity compared with the bisphosphonate alendronate. Some real-world studies argue that the cardiovascular signal is smaller than ARCH suggested. The black box warning remains on the label.

Forteo (teriparatide) and Tymlos (abaloparatide) Are daily injections of a parathyroid hormone fragment. They build bone, but the original Forteo label carried a black box warning for osteosarcoma based on rat studies showing dose-dependent bone cancer. The boxed warning was removed in 2020, though the rat data did not change; the FDA simply allowed the company to stop printing the warning. Treatment is capped at two years.

The pattern across all five drug classes is the same. Each works by sledgehammering one side of the bone-remodeling system. None of them addresses why a sixty-year-old woman is losing bone in the first place, which is tied to her sex hormones, vitamin D, vitamin K, minerals, muscle mass, and mechanical loading. Charlotte does not have a bisphosphonate deficiency.

From my book Hormone Secrets

I wrote Hormone Secrets several years ago to share what I had learned with the patients I saw. The osteoporosis chapter opens with a real woman I called Hattie. The version below is lightly cleaned up and corrected; the substance is what was in the book.

Hattie is sixty-four and works as a federal prosecutor. She is small, single, and Chinese, and lives under chronic stress. Ten years ago, her physician told her she had “osteopenia” and started her on bisphosphonate injections, then followed her with DEXA scans. The scores still worsened. When she finally needed her hip replaced, the orthopedic surgeon told her the bone was “crumbly.”

Two years ago, Hattie started a comprehensive program: estrogen, progesterone, DHEA, testosterone pellets, vitamin K, selenium, and 10,000 IU of vitamin D daily. She added ipriflavone. Since starting hormones, she has been able to handle jury trials and high-intensity legal work like an attorney half her age, and she cut her Prozac dose in half. Her repeat DEXA showed her bone density up seven percent over two years. She is starting human growth hormone and hopes to do even better.

The lesson from Hattie’s story is that treating bone disease is endocrine and nutritional, not pharmaceutical. The standard pathway treats osteoporosis as if the only issue is low bone density on a scan, then tries to push that number up with drugs that force the bone’s remodeling machinery into submission. Real treatment restores the signals the bone is waiting for.

Conventional doctors usually start with bisphosphonates. TheNNT.com summarizes the Cochrane data and concludes that the drugs do not prevent fractures in women without a prior fracture and help only a small subset of women who have both osteoporosis on a scan and a prior broken bone. The drugs cause atypical femur fractures, jawbone rotting, esophageal injury, atrial fibrillation, and dozens of other side effects. Plaintiffs filed thousands of lawsuits against Merck over Fosamax-related jaw and femur disasters. The company paid $28 million to settle twelve hundred of them.

In contrast, hormone treatment usually makes people feel better while preventing and reversing bone loss. Estrogen, testosterone, DHEA, and vitamin D all build bone. Human growth hormone alone can increase bone density by about eight percent per year in some patients.

Non-hormonal treatments worth considering include selenium 200 mcg a day; vitamin K2, which I once described as “might be valuable” and now consider essential at doses of about 180 to 360 mcg a day of MK-7; and ipriflavone 600 mg a day, an isoflavone approved for osteoporosis in Japan and sold over the counter in the US. The evidence on ipriflavone is mixed; some Italian and Japanese trials show benefit, while a 2001 JAMA trial of 474 white women found no fracture or bone density benefit and a signal of low lymphocyte counts. If a patient uses it, lymphocyte counts should be checked.

The natural history of bone loss

Bone is not a static structure. It is a constantly remodeled tissue, with osteoclasts dissolving old bone and osteoblasts laying down new bone. In a healthy young adult, these processes balance, and peak bone mass is reached around age thirty. After that, bone is slowly lost.

Estrogen levels fall sharply at menopause, and bone loss accelerates for roughly the next five to ten years. Trabecular bone in the spine and the hip is lost faster than cortical bone in the long bones. By the time a woman is in her sixties, she may have lost twenty to thirty percent of the bone she had at thirty-five. The first warning is rarely a scan; it is a fracture from a minor fall or a vertebra that compresses without trauma.

Men lose bone too, but more slowly because their testosterone declines more gradually than women’s estrogen. In men, testosterone aromatizes to estrogen, and that estrogen is what protects bone. Men who are chemically castrated with Lupron for prostate cancer lose bone quickly, which is one of many problems with it.

Risk factors for osteoporosis

• Female, postmenopausal, small-framed, of European or Asian background.

• Family history of osteoporosis or fragility fracture.

• Low body weight.

• Smoking and heavy alcohol use.

• Chronic steroid use, including inhaled steroids at high doses.

• Long-term proton pump inhibitors (Prilosec, Nexium and similar). They block the stomach acid needed to ionize calcium and other minerals.

• SSRIs and SNRIs (Prozac, Lexapro, Cymbalta and similar) have a documented association with reduced bone density and increased fracture risk.

• Chemical castration agents such as Lupron, aromatase inhibitors used after breast cancer, and methotrexate.

• Anticonvulsants and the diabetes drug class called thiazolidinediones (Actos).

• Hyperthyroidism, hyperparathyroidism, untreated celiac disease, inflammatory bowel disease.

• Sedentary life and lack of impact loading. Bone responds to mechanical stress; without it, bone goes away.

• Vitamin D deficiency, vitamin K deficiency, magnesium deficiency, and chronic low protein intake.

• Excess soda, especially cola, which is associated with lower bone density in women.

Should you get scanned?

The USPSTF currently recommends DEXA screening for all women sixty-five and older and for postmenopausal women under sixty-five with additional risk factors. The 2025 update emphasized DEXA over other modalities. For Charlotte, the question is moot; she has fractured three times in eighteen months. She is osteoporotic by clinical criteria regardless of what the scan shows, and the only utility of a scan now is to track response to therapy.

For women over sixty without prior fractures, get one DEXA scan, mostly because the result tells you whether you are looking at maintenance or whether you need an aggressive program. Repeating scans every two years or so is reasonable for tracking. Pay attention to the absolute T-score and the trend. Bisphosphonates are a failed medication class and should never be prescribed, but the other interventions here are reasonable. Ignore the term osteopenia, for this is a psych-op to sell more toxic medicines.

The scan is a brief, low-dose X-ray test. The radiation dose is about one-tenth of that of a chest X-ray. It is one of the few tests in conventional medicine that I think most women should undergo.

Vitamin D: the foundation

Vitamin D is a steroid hormone, not a vitamin, and it regulates thousands of genes involved in immune regulation and bone metabolism. The official US recommended daily allowance is 600 to 800 IU. That amount is criminally low. It will prevent rickets and almost nothing else.

Three people I trust on this topic have steadily advanced my thinking: Neal Rouzier, MD, who has kept his level around 200 ng/mL for years; Henry Lahore, the retired Boeing scientist who built VitaminDWiki.com and keeps his level at 200; and the Brazilian neurologist Ciccero Coimbra, whose ultra-high-dose protocol of about 1,000 IU per kilogram per day has produced thousands of multiple sclerosis remissions. Jeff Bowles, the polymath autodidact who wrote The Miraculous Results of Extremely High Doses of the Sunshine Hormone Vitamin D3, documents over a thousand self-experiments at doses ranging from 25,000 to 100,000 IU a day.

In my view, supported by these authorities and not by mainstream medicine, 25-hydroxyvitamin D blood levels well over 100 ng/mL are healthier than the levels most people have today. Standard guidance calls 30 to 100 ng/mL “sufficient” and tells most people to aim for 40 to 60. I think 80 to 150 is closer to right for most adults, and that some people, including those with neurological or autoimmune disease, or active infection, do better at levels even higher. I used this approach to address my own Parkinson’s after realizing my level of 120 was probably not high enough.

Comment: If you decide to push your D level high, you must take it with cofactors and monitor your blood levels. About one in ten thousand people has a genetic glitch that prevents normal regulation of vitamin D, and high doses in those individuals can cause hypercalcemia. Testing every two months while you are titrating up is cheap insurance. Most people need 8,000 to 10,000 IU a day to reach a level around 80 to 100. People with VDR receptor polymorphisms may need three to four times that amount.

On the rat poison question: D3 is used in some rodenticides at doses 40,000 to 100,000 times higher than in human supplements. Rats are tiny. The argument that 5,000 or 10,000 IU is dangerous because rat poison contains 100,000 IU per dose is the same logic as saying water is dangerous because you can drown in it.

Vitamin K2 is Essential.

In my book, I wrote that vitamin K “might be valuable” for bone. That sentence undersold it. Vitamin K2 is essential for both the bone effect of vitamin D and for keeping calcium out of the arteries while putting it into bone.

Vitamin D3 increases calcium absorption from the gut. Vitamin K2 directs calcium to where it should go. Without enough K2, the calcium mobilized by vitamin D is more likely to end up in arterial walls than in the trabeculae of bone. K2 activates osteocalcin in bone and matrix Gla protein in arteries; both proteins require K2 to function.

The 3-year randomized MK-7 trial in 142 postmenopausal osteopenic women, with vitamin D and calcium in both arms, showed that 375 mcg of MK-7 daily reduced undercarboxylated osteocalcin by sixty-five percent and improved bone microarchitecture. A 2022 meta-analysis of sixteen K2 trials in postmenopausal women showed improved lumbar spine bone mineral density. Knapen and colleagues showed that 180 mcg/day of MK-7 over three years preserved spine and femoral neck density.

The Japanese standard osteoporosis dose is 45 mg/day of MK-4, about a hundred times the typical Western K2 capsule. The US and most of Europe have settled on much lower MK-7 doses (180 to 375 mcg). [Note for emphasis: there are 1,000 micrograms in one milligram, so a milligram dose is huge compared to a microgram dose.] I take a high-dose K product such as Life Extension’s Super K, which contains MK-4, MK-7, and K1. Anyone who takes vitamin D in meaningful doses without K2 is missing the second half of the equation.

The mineral cofactors

Magnesium. Probably eighty percent of the population is deficient because industrial farming has stripped the soil. Most magnesium is stored in bone and soft tissue, so blood tests miss the deficiency. High-dose vitamin D depletes magnesium quickly. Heart palpitations, panic attacks, restless legs, leg cramps, and fatigue on high-dose D are usually due to magnesium deficiency, not D toxicity. Take 400 to 800 mg a day of magnesium glycinate, citrate, or threonate. The only common side effect of higher doses is loose stools.

Boron. In regions with boron-rich soil, arthritis and osteoporosis are uncommon. In boron-poor regions, both diseases are widespread. Rex Newnham’s work in Australia documented that 30 mg of boron twice a day cleared arthritis within months. The US and EU have made boron supplements hard to get, with doses limited to near-homeopathic 3 mg. Borax (sodium tetraborate) is freely available, food-grade (you eat the laundry detergent in small quantities), and supplies plenty of boron when used in tiny amounts. I take a quarter teaspoon daily, mixed into table salt.

Zinc. About a third of people worldwide are zinc deficient. Zinc is required for vitamin D receptor function and thymus health. Take 15 to 40 mg daily, ideally with copper if you take it long-term, since zinc depletes copper.

Selenium. Selenium status is inversely correlated with osteoporosis in observational studies; in a recent analysis, postmenopausal women in the highest dietary intake quartile had dramatically lower odds of osteoporosis. A randomized trial of 200 mcg/day for six months did not change bone turnover markers in postmenopausal women, so the data are mixed. A reasonable dose is 200 mcg a day; some clinicians start higher for a month and then drop back. I sometimes get mine from 3 Brazil nuts a day, which puts me in roughly that range without a pill.

Comment: Two minerals to avoid. I do not recommend supplemental calcium, ever. The body extracts more calcium from food than most people realize, and pushing more calcium in capsule form tends to deposit it in arteries and kidneys rather than bones, especially in the absence of adequate K2. I also avoid supplemental iron. Adult diets add about a milligram of iron a day to the body’s stores over a lifetime, which is inflammatory, and Parkinson’s patients have excess iron in the substantia nigra. I donate blood for that reason.

Hormones: the real first-line therapy

Estrogen rebuilds bone in postmenopausal women. The Women’s Health Initiative scared a generation of women off estrogen by misrepresenting an oral conjugated equine estrogen plus synthetic progestin combination as bioidentical hormone replacement. It is not. Properly dosed bioidentical estradiol, given orally or as a pellet, along with bioidentical progesterone, is the single most powerful pro-bone intervention available to a postmenopausal woman. Estradiol in patch form is inadequate for bone improvement, and if this is desired, it should be given along with oral estradiol. Estrogen benefits include better mood, sleep, cognition, skin, and libido, as well as lower all-cause mortality when started near menopause.

Testosterone builds bone in both sexes. In women, low-dose pellets or troches restore libido, energy, and lean mass, with a bone-building effect. In men, restoring testosterone to the upper end of the normal range protects the hip and spine and lowers the risk of frailty fractures.

DHEA is a precursor adrenal hormone that drops sharply with age. At 25 to 50 mg a day in women and somewhat higher in men, it tends to support bone and muscle along with mood and energy. It is harmless and can be given in multi-hundred mg doses to elders in order to relieve arthritic symptoms.

Progesterone, when given as oral micronized progesterone, has a modest pro-bone effect on osteoblasts and is useful for sleep and anxiety. While progesterone cream can relieve some symptoms, it is ineffective in treating osteoporosis because its half-life is only an hour.

Human growth hormone has been shown to increase bone density by several percent per year in some studies. It requires injection, is expensive, and is overregulated in the US. Peptide secretagogues such as ipamorelin or sermorelin can stimulate the patient’s pituitary and produce part of the same effect at a fraction of the cost and regulatory risk.

Hattie’s seven percent gain in two years on hormones shows what is possible. That is a faster rate of bone gain than almost any drug produces, and the patient feels better throughout. The contrast with the fatigue, bone pain, and dread that usually accompany Fosamax could not be sharper.

Whole-body vibration: the device that grows bone without drugs

Bone is a “piezoelectric” tissue. It responds to mechanical loading by laying down more matrix at sites of strain. NASA documented this in reverse in zero gravity: astronauts lose bone rapidly in orbit, and they need targeted mechanical stimulation to recover.

Clinton Rubin and colleagues at Stony Brook discovered that low-intensity, high-frequency vertical vibration (around 30 to 90 Hz at very small accelerations, well under one gravity) stimulates bone formation through the same mechanotransduction pathways. Simply standing on a properly engineered platform for ten or twenty minutes a day signals to bone that it is being asked to support a load. This signal is enough to slow or reverse postmenopausal bone loss in some women without any drug.

The Marodyne LiV platform is the device built on Rubin’s research. It vibrates at 0.4 g, low enough to be safe for people with osteoporosis and far below the gym-style “Power Plate” devices that run at 1 g or higher and carry contraindications. A 2016 meta-analysis of low-magnitude whole-body vibration in postmenopausal women showed improved lumbar spine bone density and fewer falls. The technology will not match what hormones and a serious resistance program can do, but it is genuinely additive, especially for someone like Charlotte who cannot yet load her spine aggressively.

Resistance training and impact: the LIFTMOR data

The LIFTMOR trial from Australia enrolled postmenopausal women with low bone mass and put them through twice-weekly heavy resistance and high-impact training: deadlifts, overhead presses, back squats at 80 to 85 percent of one-repetition maximum, plus jumping chin-ups with drop landings. (This is very aggressive and more than I can safely do now at 72.) After eight months, the lifting group had increased bone at the spine and femoral neck and improved functional performance, while the control group lost bone. There were no fractures. The lesson is that heavy resistance training, properly coached, is safer for fragile bone than the protective non-loading regimens most older women are sent home with.

Charlotte is sixty and otherwise healthy. She should lift heavy loads under supervision two or three times a week. Walking is not enough; even brisk walking does not provide the loading signal bones need. Hopping in place when she can tolerate it, climbing stairs, jumping rope on a soft surface for short intervals, and progressively heavier deadlifts and squats with a coach who understands the LIFTMOR protocol will do more for her bones than any drug.

Other supplements with mixed evidence

Ipriflavone is a synthetic isoflavone that inhibits bone resorption and stimulates osteoblasts. It is approved in Japan and Italy for osteoporosis at 600 mg per day in three divided doses and is available over-the-counter in the United States. Italian and Japanese trials at this dose show preservation of bone density and modest gains in postmenopausal women, with vertebral fracture reductions in some studies. A 2001 JAMA trial in 474 white American women showed no benefit and a real signal of low lymphocyte counts in about thirteen percent of users. If a patient takes ipriflavone, lymphocyte counts should be checked every few months. Hattie tolerated it well.

Strontium. The prescription form, strontium ranelate, increased cardiovascular risk and was eventually withdrawn from much of Europe. The over-the-counter form, strontium citrate at 680 mg a day, has been widely used in the integrative world. Strontium substitutes for calcium in the bone matrix, inflating DEXA bone density readings by atomic mass alone. Some of the apparent benefit on a scan is artifact. The actual fracture-prevention data for strontium citrate are weak. I do not recommend strontium.

Silicon. Horsetail extract or orthosilicic acid provides bioavailable silicon, which supports collagen cross-linking in bone. The evidence is modest. It is inexpensive and has no obvious downside. As a side benefit, silicon binds aluminum in the body and can help eliminate it. You can buy Living Silica liquid on Amazon or better yet, drink Fiji silica water, a liter a day.

Collagen peptides. Hydrolyzed collagen at 5 to 10 grams per day has shown benefits for bone density and bone matrix in postmenopausal women in randomized trials. It is also beneficial for skin, joints, and connective tissue.

Sun. Direct sunlight on bare skin, taken regularly and without sunscreen on as much skin as possible, produces vitamin D in the body in the form of D3 sulfate, which supplements cannot match, and triggers the release of nitric oxide and other beneficial molecules. Sun avoidance is one of the great public health blunders of our era. The skin cancers that scare people are mostly squamous and basal cell, which are easy to remove and rarely lethal; the lethal kind, melanoma, is more common in people who get little sun than in those who get a lot.

What this means for Charlotte

Three fragility fractures in eighteen months mean Charlotte’s skeleton is in trouble right now. Her doctors’ “osteopenia” label is meaningless nonsense. In a just world, giving her a bisphosphonate or related drug would be a criminal act. She needs:

• A full bioidentical hormone workup and replacement: estradiol, progesterone, testosterone, and DHEA, with a clinician who knows how to dose them. Oral estradiol; oral micronized progesterone; testosterone cream or pellets; DHEA 25 to several hundred mg. This is by far the most critical step, along with vitamin D, K2, and magnesium. The rest is window dressing.

• Vitamin D3 at a starting dose of 10,000 IU daily, with the goal of raising her 25-hydroxy level to 80 to 120 ng/mL, with blood checks every two months until stable.

• Vitamin K2. 180 to 360 mcg of MK-7 daily is conventional as part of a multi-K product such as Life Extension Super K, but if you look for it, you can find products with 45 mg per capsule.

• Magnesium glycinate 400 mg twice daily, boron from borax in daily doses, zinc 25 to 30 mg daily, selenium 200 mcg or five Brazil nuts daily.

• Use a whole-body vibration platform, such as the Marodyne LiV, for ten to twenty minutes a day. This is a useful piece of equipment, not a gimmick.

• Twice-weekly progressive heavy-resistance training with a coach who understands the LIFTMOR protocol, plus impact loading as her healing allows.

• No calcium supplements. No bisphosphonates. No Prolia. No SSRIs, if at all avoidable. No proton pump inhibitors unless absolutely required.

• A repeat DEXA in twelve months to track progress, with the understanding that the trend matters more than the absolute value.

If Charlotte does this and stays patient, the available evidence and my own experience with patients like Hattie indicate she should hold or measurably improve her bone density within a year, and she should feel substantially better throughout. The pharmaceutical alternative is to be slowly poisoned for a decade, with worse bones at the end and a jaw that may rot.

The hard part is finding a clinician who will help her. Consider nearly retired physicians, anti-aging clinics experienced with bioidentical hormones, and a small number of integrative practices. Most conventional internists and gynecologists will fight her every step of the way. That is not a comment on their character; it is a comment on what they are trained to do. Clinicians at WorldlinkMedical.com have been trained as I have, and many of them can be very helpful. A lot of them are nurse practitioners, and they’re fine too.

Charlotte, this one is for you.

I am grateful to my free and especially my paid subscribers who support my work. Please thank me with comments if you cannot afford a paid subscription..

This problem is ubiquitous, and your friends need to learn about it.

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106 Comments

  • Avatar Steve Belleci says:

    My wife was diagnosed with Osteoporosis when she was 50 years old. The Kaiser Doctor said it was the worse case they had seen on the scale. We saw an article about Standard Process Calcifood Powder. She started taking that immediately. Within 6 months she started feeling better and after one year her test was normal. She is 70 now with no bone problems and takes no medication. She does the D3 & boron and the Calcifood powder maintenance dose.

    • Avatar Robert Yoho, MD says:

      A woman of that age who is not using testosterone cream is wasting her energy.

    • Avatar Christine says:

      I learned thru research that We must also supplement with Collagen when taking calcium so that the calcium is deposited in the bones and not the arteries/ blood vessels

      • Avatar Robert Yoho, MD says:

        Read Hormone Secrets and this blog for my complete opinions about supplements that improve osteoporosis.

  • Avatar Bronc Buster Self-Healing says:

    Dear Doctor Yoho, since you are open-minded and don’t mind changing your mind when needed, I have confidential suppressed far out of the ordinary unbelievable wellness reality for you.

  • Avatar BethanyAnne says:

    I was diagnosed with osteopenia years ago. I researched Fosamax (I always research prescription drugs before I even fill them), tossed the scrip, and never had another bone density scan. Upped my D, K2, mag, boron, selenium (I take in the form of brazil nuts, as the pills always cause pain), got my hormones looked at, and started lifting weights and doing yoga and cardio.

    Last year, I had a really bad fall, fell solidly on my left hip with some force. Really bad fall. Hip should have broken. Much to my amazement, I only had some slight bruising (I take a lot of C). So much for the osteopenia diagnosis. I should have had osteoporosis by now, by their reckoning. My faith in modern medicine is VERY selective.

    Just a note on almonds and prunes – Dr Michael Greger (yeah, yeah, I know) came across some studies that one inhibits osteoclasts (the tear down ones) and the other stimulates osteoblasts (bone builders). Can’t recall which was which, but he has some videos on it on nutritionfacts.org. Fortunately, I really like almonds and prunes.

    • Avatar pretty-red, old guy says:

      YOU are a great independent thinker.

      I wish my wife had done the same. . . was on Fosamax 4 yrs. Lucky so far, no falls to test it!

      • Avatar BethanyAnne says:

        LOL…I don’t know that I’m all that, but I’ve been deeply suspicious of the medical/pharmaceutical complex for decades.

        • Avatar pretty-red, old guy says:

          well you are at least 2 decades ahead of me. . . and most!

          • Avatar BethanyAnne says:

            Well, you’re posting on this substack, so you’ll be catching up pretty quickly. I’d also recommend “A Midwestern Doctor” substack, and “Curious Outlier”. Very educational health information. I found out about DMSO on AMD, and a lot of good information about Chlorine Dioxide on CO. With just those two things, you can heal A LOT of medical issues. I have a whole bunch socked away for the day the FDA decides “it’s too dangerous for the public to use” (brought to you by Pfizer!). I mostly look to Yoho for his info on supplements and hormones, but I do enjoy his articles where he rags on what the medical/pharmaceutical complex is up to at any given time.

          • Avatar pretty-red, old guy says:

            yep, I’m with ya’. I have subscribed to MW Doc, Yoho and a number of others. Got my DMSO and Methylene Blue socked away too!

            Yoho is a good guy. Admitted last week he made errors in a post, authentic.

          • Avatar BethanyAnne says:

            LOL! My brother from another mother!

  • Avatar angelhalo says:

    the demons running these corporations never miss an opportunity to torture and poison humanity.

  • Avatar Wise Old Woman in the Woods says:

    Would breast implants cause any autoimmune issues that might be linked to brittle bones?

    • Avatar Roger says:

      Unbekoming has a substack about breast implants:

      These were not fringe findings from a dissident laboratory. This was the manufacturersu2019 own data, collected under FDA mandate, analysed by university researchers, and published in the Annals of Surgery. The largest cross-sectional study to date, by Watad et al., independently corroborated the pattern: among 24,652 silicone implant recipients compared to 98,604 matched controls, the hazard ratio for any autoimmune or rheumatic disorder was 1.45.u00B2 The signal was consistent across independent datasets, different methodologies, and different research teams. The very studies designed to prove the product safe had demonstrated that it was dangerous.

      https://www.unbekoming.com/p/the-bag-of-silicone-garbage

      Odds ratio of 1.45 means it was 45% higher than normal rate.

      • Avatar Robert Yoho, MD says:

        It seemed worse than that when I was in practice and doing breast implants. They all seem to get hard, which is inflammatory.

        • Avatar Roger says:

          They must have greased a lot of palms at FDA to get such a toxic procedure re-approved 14 years after it bankrupted DOW. I see that the IOM was up to its Three Wise Monkeys standards of “we see no evidence of hazards”, hear no evil, say no evil. They didnt see the evidence because few were looking for it.

          • Avatar Robert Yoho, MD says:

            The FDA gets over half of its revenue through user fees, which are almost a direct kickback to pharma. User fees are produced during the drug approval process. So the FDA is essentially completely bought off.

    • Avatar Roger says:

      Here is study showing a relationship between bone density and ulcerative colitis.

      https://pmc.ncbi.nlm.nih.gov/articles/PMC10484226/

      The official position:

      Osteoporosis: Is It an Autoimmune Condition?

      Osteoporosis is not an autoimmune disease. However, research suggests a malfunctioning immune system may cause osteoporosis. Scientists are studying this link between changes in your bones and your immune system.

      https://www.healthline.com/health/is-osteoporosis-an-autoimmune-disease

    • Avatar Maha says:

      Here’s a question Dr Yoho could shed light on better than anyone. I’d hazard a WAG and say if they are from the old silicon, maybe. The saline, not sure.

      • Avatar Robert Yoho, MD says:

        Spleens cause far fewer problems, but they sometimes cause breast implant illness, and mature women should get rid of them.

    • Avatar Robert Yoho, MD says:

      Get rid of those breast implants. They could be causing super big problems. You need to get them dissected out with the material around them, and this is called an en bloc resection. It takes a skilled surgeon to do it, and I have two referrals in my post about that.

      • Avatar Roger says:

        I was wondering how you would take on this issue given your history as a plastic surgeon. Glad you are taking it head on.

      • Avatar Wise Old Woman in the Woods says:

        No breast implants for me! I have a friend who has breast implants and has been complaining about something bone related. Eons ago, I worked as a new attorney on the breast implant litigation on the defense side. I remember thinking the allegations made a lot of sense even though our ‘experts’ labeled the women as kooks.For the three years that I did medical defense going through medical records, I was always struck by how many procedures the patient/plaintiff had undergone. I concluded that the risk of a bad outcome seemed correlated to having had many procedures. From the experience I stayed away from allopathic medicine. I’ve been told how weird it is that I have never had surgery (except for the resetting of a broken nose). For a healthy society, the inverse should be weird.

  • Avatar pretty-red, old guy says:

    from the MK7 reference / link above:

    Conclusion: Treatment with MK-7 375 u03BCg daily as an add-on to calcium and vitamin D increased carboxylation of osteocalcin. However, treatment of postmenopausal women with osteopenia for 3 years did not affect biochemical markers of bone turnover, bone mineral density, or bone microarchitecture.

    This appears to conflict with your conclusion there. . . Did I miss something?

  • Avatar Jim U says:

    Thank you. Especially for clearing up the argument about vitamin D being rat poison. Iu2019m now reading negative articles on vitamin K. Thereu2019s too much information out there, itu2019s hard to know what to believe.

    • Avatar Maha says:

      It is almost axiomatic. Vitamin D, modulating 3000 + biochemical actions in the body, and insuring good outcomes in a myriad of physiological responses to everything from sun exposure to pregnancy, and K, especially the bone building effects of K2, wind up being trashed by obedient “health writers” in the pay of Pharma companies whose balance sheet might be minimally challenged by smart consumer choices.

  • Avatar fits6 says:

    🙂 So happy you are exposing the lie of osteopenia. You opened my eyes. You either have porous bones or you don’t. Great information once again. Will you come speak at my event?

    • Avatar Robert Yoho, MD says:

      I would if I were completely well, but I’m kind of sick now, and I’m trying to recover. I have a lot of projects in the works. Thanks for the compliment of the invitation.

  • Avatar Roger says:

    The Unbekoming substack is not a big fan of osteoporosis medicine including the DEXA scans:

    The DEXA scan measures bone mineral density. That is all it measures. It cannot assess the collagen matrix. It cannot tell you whether the scaffolding onto which those minerals are deposited is strong, supple, and intact or degraded and crumbling. It measures the bricks and says nothing about the frame.

    https://www.unbekoming.com/p/osteoporosis-bad-aim

    • Avatar Maha says:

      It cannot visualize the actual mineral matrix, which is often been pumped up on big atoms of calcium and Phosphorus, creating hydroxyapatite, providing hardness and rigidity, with poor fill in from Magnesium, Strontium, Boron…

  • Avatar Maha says:

    Once again, Bio-identical HRT, a little common sense with diet and of course exercise if feasible, appropriate D3 intake and absorption, and much of what ails those filling PCP’s and specialist’s waiting rooms would diminish from screaming madness to a low roar.

  • Avatar Roger says:

    Dr Osborne is also not a fan of DEXA scan and suggests the following:

    The Best Medical Tests To Evaluate Bone Health & Osteoporosis

    https://www.youtube.com/watch?v=j6R7Ik1Hr5o

  • Avatar zeb11 says:

    I broke my right wrist after an awkward fall aged 50. It required open reduction and internal fixation. They gave me a bone density scan but could not find a cause. Fast forward 5 years…..diagnosed coeliac disease. Bingo!

  • Avatar Jody Eddings says:

    Many yrs ago, I heard Dr John R Lee on the radio (podcasts of the time) talking about progesterone (cream) increasing bone density. I told my mom, and her bone density increased within 6 months – though I donu2019t know exactly how much, or if she was on any other HRT. But, she was extremely delighted that it resolved her incontinence too.

    I shared that with a coworker at UCDavis, who was about to have corrective surgery for it – she was mid-40u2019s and physically active, but she u2018leakedu2019 when she jogged. She ended up cancelling the surgery

  • Avatar Vi says:

    Hi Dr. Yoho,

    I know this comment is ‘off topic’, however, I REALLY want to let you know about a natural herb that converts ‘L-dopa’ into Dopamine! It’s called ‘Mucuna Pruriens’ also known as ‘Velvet bean extract’ or powder…….It can really boost our own dopamine levels in the body, and can help Parkinson’s patients! I hope this info interests you enough to look into this a bit (or a lot)……..I would be DELIGHTED if it could help you even somewhat! I think that you may be doing other things to alleviate your condition, but perhaps you could take this herb (if you approve of it, after researching it) along with other modalities you may be doing. I wish you much luck in your journey to heal!

    • Avatar Butterfly2510 says:

      Interesting. Can you tell us more? Are there studies or research you can share?

      • Avatar Vi says:

        Hi Butterfly2510

        So, I just did a quick search regarding your question, and I found a site called:

        ‘Cobfoundation.org’ 4-benefits-of- and-side- effects-of-mucuna-pruriens

        I will look for more, and just learned about this on my own, and I don’t know if you do any research at all, but if there are studies on this, you may find them easily. It is very interesting, I agree, and would like to learn more, like you, and thanks for your interest!

        • Avatar Vi says:

          So, I clicked on the link I gave and found it’s more about bladder health, however there was an article about ‘Food grade Diatomaceous Earth’. I found a better website that has a lot of good information on it at:

          nothingsincurable.com/everything-about-Diatomaceous-earth It is VERY HIGH in silica, and this article explains exactly what this ancient compound is. I think the high silica content is why it is so very good for bone, skin, nails, and hair health. I hope this helps……worth looking into anyways, as there’s so many purported benefits…..I will dig further, and hope others that are intrigued will also. Best 2 u all!

        • Avatar Vi says:

          Whoops! My mistake…..I meant to post a link to a website explaining more about the affects of the herb ‘Mucuna Pruriens’ on Parkinson’s disease as that is what ‘Butterfly’ user asked for…….so here is a link that gives a little more information on this herb…https://www.carenity.us/condition-information/magazine/news/mucuna-pruriens-what-are-the-benefits-for-parkinsons-disease-1762. I hope this helps give a bit more understanding of this herb and how it can help boost ‘Dopamine’ production in the brain.

    • Avatar Robert Yoho, MD says:

      My naturopath has prescribed this for me, but I appreciate your interest and your help.

  • Avatar Vi says:

    I’ve recently started taking ‘Diatomaceous Earth’ and if the health claims about it are true, then it is a POWERHOUSE of health benefits…….(I’m really hoping this is so). Apparently, it is great for bone health, skin, hair, nails, chelating aluminum, and other heavy metals from the body, and ‘bad bugs, and candida’ don’t LIKE IT!……..boosts the immune system, helps our heart health (through improving collagen in the body), and many other benefits…….It sounds almost too good to be true, but nature is amazing, and all these benefits are possible. I’m keeping an open mind……..I will pray for your friend, and hope she is researching and learning about all these different options that can improve her bone density safely!

  • Avatar Butterfly2510 says:

    Thank you for helping women to understand the lies involved in an Osteopenia diagnosis and how horrible the drugs are to treat it! Thereu2019s so much confusion and most people donu2019t have the time to research it.

  • Avatar Diane says:

    Excellent article once again, thank you. Unfortunately for Australians the corrupted and evil TGA have banned DHEA, and of course hormones can only be supplied by the medical cartel, who, if they prescribe estrogen at all, can not prescribe it for long due to the supposed risk of breast Cancer. Someone I know had their breasts removed in order to stay on HRT.

    I always remember that bone health is ultimately about pliability, flexibility, dynamic strength under load, which is different from just density. You can have a really dense yet brittle bone that is dynamically useless.

    Regards the soda – It is not all soda drinks but those containing Phosphoric acid, which requires mineral buffering. According to Joseph Pizzorno diet induced cellular acidosis (not acidemia) is also a cause of reduced bone health and bone resorption. Blood pH normal range is 7.35-7.45. The term acidosis referring to a process, an ongoing trend toward acidemia, without neccesarily reaching a blood pH less than 7.35, which would be frank acidemia. Western diet is associated with low grade chronic metabolic acidosis, at the lower end of normal, whereby a constant low grade stream of buffer minerals are removed from bone and tissues to keep blood within livable range. Because pH is logrythmic, even tiny changes in pH reflect large changes in hydrogen ion concentration and therefore buffer ions required. NEAP (net endogenous acid production) must equal NAE (net acid excretion) which is how dietary acid production can be measured, even being able to change the diet in order to solve for urinary pH problems. In-vitro studies show bone degrading osteoclasts to be almost inactive at a pH above 7u00B74. Reductions of 0.1 in pH can cause a doubling of bone resorption pit formation. Extracellular hydrogen ions, indicating low grade blood acidosis, are a trigger for active bone resorption, and inhibit mineral deposition by osteoblasts. Vit-D deficiency contributes to metabolic acidosis via reduced calcium absorption, and therefore mineral buffer activity. Magnesium is also lost in higher amounts in acid forming diets, so if Mg supplementation is not helping, look to dietary pH.

    Including excretion of excess acid factors, the kidney adapts by decreasing excretion of citrate in an effort to maintain alkalinity which increases the risk of calcium oxalate stones, and possibly sub clinical damaging crystallisation in the nephrons. Dietary acid load is shown to correlate with chronic kidney disease, and bicarbonate supplementation slows decline.

    People criticise the idea of low grade chronic acidosis because blood pH remains consistent. But, now small changes can be detected, and a level of 7.35, though still ‘normal’ is practically sginificantly different from 7.45. And, they evidently never ask how the blood maintains a stable pH with net acidic inputs, as if the minerals were beamed in from outer space. The mechanism no doubt ties in somehow with K2 and osteocalcin and matrix gla signalling.

    Independant of calcium intake or Vit-D, potassium citrate or even potassium bicarbonate significantly improves calcium balance, bone density markers, microarchitecture and fracture risk. Potassium bicarbonate is twice as effective as sodium bicarbonate. Also, in a high salt diet, potassium citrate prevents the increased excretion of urine calcium and the bone resorption markers caused by a high salt intake. Potassium magnesium citrate also counters renal stone formation and significantly retards crystallization of calcium oxalate vs. placebo.

    An alkali diet, with vegetables provides requisite mineral buffers and potassium base will improve bone health. But, for those that dont eat vege, even potassium citrate supplement on its own can help. Lemon juice each day provides the citrates which are also used as a base. I like to tell people this acid/base piece because, beyond hormones, this is something everyone can do easily for themselves – eat more veges, drink a daily lemon juice, increase thier potassium balance.

    Don’t ask me how any of this relates to those on a carnivore diet, which is all acid forming. Then again, those long term fruitarian athletes and bodybuilders, eating little to no protein would also seem to defy understanding!

    • Avatar Robert Yoho, MD says:

      Diane, you need to start a Substack and send it to all your contacts in your phone, with a disclaimer that they can unsubscribe any time. Read my articles about writing by searching for writing in the upper right-hand corner of my Substack in the search bar.

      • Avatar Diane says:

        Thank you Dr Yoho, this is high praise indeed! If I had the imagination for continuous useful content, and writing didn’t stress me out so much, I would consider doing that.

  • Avatar Jody Eddings says:

    You may already be aware of this (link below) – connection of Aluminum toxicity and Parkinsonu2019s .

    I am detoxing Aluminum right now, especially as I found out that the makeup Iu2019ve been using DAILY for about 30 YEARS – contains Aluminum!

    Detox using Silica, found high in FIJI water at 93 mgu2019s per liter. Silica binds tightly to AL in the body (and bones) and is then excreted.

    Aluminum is toxic, cumulative and inflammatory.

    (Also ref Dennis N Crouse – book – Discovering Magic in Water)

    https://substack.com/@drchristopherexley/note/c-205378398?r=1t1mj8&utm_medium=ios&utm_source=notes-share-action

  • Avatar Fred Watkins says:

    Thank you for a very informative article.

    I have tried Magnesium glycinate and found it to give loose stools. I am a fit 84 year old and would like to avoid this terrible inconvenience; what about Mg orotate – it is also good for treatment of heat arrythmia and has no loose stool side affect, but not sure if it would do essentially the same job as glycinate? Would appreciate your opinion on this.

    Thanks for your kind attention, John

  • Avatar LINCOLN LOVER says:

    Thank you Dr Yoho for this much needed article. I was told I had osteopenia which then progressed to osteoporosis. The Dr. wanted me on Fosamax but I researched it and found women who took it were calling it poison and to stay far away from it. I tried some more natural products but I could not tolerate them because of the strontium in them. Then I continued researching and found quite a few Drs were aligned on taking Vit D, K2,boron, magnesium and eggshell calcium. So I started to do that regimen, I think, with success. I make my own eggshell calcium capsules to take with the other supplements. My nails really show the difference because they were getting very thin and always splitting. I never drank milk as a child nor now either so I have had the results of that in my teeth and nails and I thought , my bones. But I have fallen and never broken any bones, Thank God!!! Now I don’t know what to think.

    I had a full left hip replacement 3 years ago. The surgeon never said anything negative to me about my bones. It was a success but I would have rather been able to do something about arthritis than have any surgery. I do have RA in my hands now. That is my next project, to rid myself of this!

    I am going to get some Brazil nuts asap!

  • Avatar Jack Abney says:

    Great article on bone health. I am sharing this with my sister and daughter-in-law. Thank you for writing it and sending it for free.

    At 88 years, I thank God for guiding me in my 76 years of efforts to stay strong and healthy. My smart watch rates me as being 64 years fitness age, which I find is hard to believe after a misdiagnosed lung cancer lobectomy. Your book “Butchered by Healthcare” was needed long ago.

    Jack

  • Avatar Radiance says:

    Estrogen question:

    My doctor, who has Dr. Rozieru2019s book in her office, told me I shouldnu2019t take oral estrogen due to blood clotting factors and venous issues. She suggested an estrogen patch instead. Iu2019d love to hear your thoughts, Dr. Yoho.

    • Avatar Robert Yoho, MD says:

      The patches do not work very well, although they are symptomatic relief. For real osteoporosis improvement and other advantages, you need oral estradiol. Don’t get too excited about theoretical risks. I’m telling you what I would do, and I’m not offering medical advice.

      • Avatar Radiance says:

        Thank you, Dr. Yoho. I appreciate you taking the time to answer my question.

        P.S. your boron post has been super helpful!

  • Avatar Crixcyon says:

    …”In the last eighteen months, Charlotte has fractured her ribs, broken her wrist, and experienced a spontaneous vertebral collapse.”…sounds exactly like my 80 year old wife over the last two years. She had been taking Prolia for about 6-7 years. According to the witch-doctors who prescribed that garbage, her bones should have been stronger or at least not deteriorating.

    You can never trust doctors, big pharma or the swine that promote them. As far as health goes, these people are 110% clueless and it shows with all their crappy info and recommendations.

  • Avatar Christine says:

    I found research online about people who strengthened their bones with small doses of BORAX daily!! It has been recorded that people who supplement with this substance which has been labeled as poison ( IT IS NOT) Were able to strengthen their bones to the point of it making it more difficult for surgeons to cut thru the bones!! I knew about BORAX for a long time but when I decided to research it, I was completely surprised what I found!!

    ANOTHER CHEAP, NON PATENTNABLE SUBSTANCE THAT BIG PHARMA DOESNT WANT PEOPLE TO KNOW ABOUT! I am not suggesting that anyone take it but Please DO YOUR OWN RESEARCH!!

    I put 1/8 tsp in my coffee in the morning!!

    All it is: PURE MINERALS

    • Avatar LINCOLN LOVER says:

      I put a pinch in my coffee too but yesterday I bathed in Boraxo and epsom salts. I have been doing this for years. Maybe the borax is responsible for helping my bones!! I do take boron capsules with other supplements for my bones along with eggshell calcium. My nails are finally much better, having been thinner and splitting.

      • Avatar Robert Yoho, MD says:

        Boron capsules are typically only 3 mg. You need much more, ideally. Read my Boron post.

        • Avatar BRobi says:

          I started my spouse on 6mg/day….which is low. But, for the first time in the 45 years I’ve known him, he says his knees no longer ache every night. That’s a big win for him! He might become Superman if I start lacing his coffee with my laundry booster…..

          • Avatar Christine says:

            After researching BORAX, I put 1/8-1/4 tsp in my coffee every morning, the poison label is a big fat LIE so people don’t discover that it heals arthritis!! There was a doctor in the 50’s or 60’s that tested it on himself first and after discovering it worked to heal his arthritis, formulated a capsule and sold 10,000 bottles, the problem came after he asked for help from a friend in the pharmaceutical industry where he was found out for helping people heal themselves with a cheap and effective product called BORAX. The FDA & AMA fined him and shut down his operation and they put a poison label on BORAX!!!

          • Avatar LINCOLN LOVER says:

            Yes! I know this story. I was a bit fearful of using that much in my coffee at first as people seem to report that they can not feel well with too much. I will keep upping my pinch to see how I feel. Thank you!!

          • Avatar Christine says:

            You’re welcome, Information is POWER uD83DuDC96uD83EuDEC2

        • Avatar LINCOLN LOVER says:

          Yes, thank you!! I read your Boron post but I think I will read it again.

    • Avatar Robert Yoho, MD says:

      I take a half teaspoon a day for my ankle arthritis, along with two tablespoons of DMSO. I’m going to pin this to the top. Thank you for your comment.

  • Avatar Sara Buscher says:

    K2 should be in the form of MK7 to direct calcium to bones.

  • Avatar Alysson says:

    I used to get DEXA scans. My last two bone tests have been with a technology called REMS (Radiofrequency Echographic Multi-Spectrometry). It involves a radiation-free ultrasound-based technology that assesses bone strength and bone mineral density.

    Dr. Andy Bush in Sanford, NC is a former orthopedic surgeon who performs REMS testing. Hereu2019s a video with Dr. Bush that discusses the REMS technology: https://www.youtube.com/live/v0tclg8LYAo

    Currently, Europe has more practitioners who offer REMS testing than in the United States.

    Per DEXA, I have osteoporosis. Per REMS, my bone strength is u201Cin the green,u201D meaning my bones are strong and my risk of fracture is low. Iu2019m petite and in my 60s. Last year, I had a nasty fall that hurt like hell. If my bones were fragile, I would have had a break in my right wrist. Just to be sure, I had a x-ray of my wrist. No fracture.

  • Avatar LJinTX says:

    Excellent information!

    Some questions – Iu2019m being given Xgeva which you didnu2019t mention. Iu2019m also in treatment for breast cancer – anti estrogen enhertu. No doctor will prescribe hormones for a u2018hormoneu2019 dependent cancer. Localized estrogen is just that – localized. If testosterone converts to estrogen – also no go. I did not know about the liftmor program – good info! I do everything else. How bad is Xgeva? And how effective is u2018everything elseu2019 without hormones?

    • Avatar Robert Yoho, MD says:

      If it were me, I would take large doses of testosterone and progesterone, which counter the cancer and do not stimulate it. Read Hormone Secrets for more. I don’t know about the drug you mentioned, but my intuition is it’s dog shit. This is just what I would do and not medical advice for you.

  • Avatar Robert Aldrich says:

    Check out Dr Hans Nieperu2019s products, for instance, calcium orotate, which a friend of mine after some time on that, happily showed me her gum-line cavities were all growing in brand-new, perfectly white calcium! In Nieper’s literature, it was commented that patients on this supplement for 2 years and then tested, had the hardest bone observed, or something to that effect.

    There is another version called membrane complex formulated for a different purpose.

    • Avatar Robert Yoho, MD says:

      Thank you for the info, I am going to investigate this because I have on my list to write a post about tooth regeneration. What I know about is DMSO and chlorine dioxide held inside the mouth three times a day, and that seems to work.

      • Avatar Robert Aldrich says:

        Really! I’m taking CDS now for many months, for a lung/sinus infection, which seems to have resolved now. Borax I take 2 pinches daily in 16 oz of juice, electrolytes, and club soda. (Delicious with ice, sipping it all day in hot weather!)

        Years ago, I ALSO rid myself of gumline cavities using calcium orotate. And at 79, I had a very bad fall in the rain on a slippery sidewalk. Nothing broken!

  • Avatar Sam Piazza says:

    Dr Yoho,

    Do you ever do Tele-Med appointments?

    My wife is on Prolia for Osteoporosis.

    No falls, but we are aware if risks, longer term.

    Looking for guidance on any u201Cbest practicesu201D for off ramp

    • Avatar Robert Yoho, MD says:

      I don’t do medical consultations, but I can chat informally. I prefer it if you are a paid subscriber, Sam. You can email me at [email protected] to hook up. I am super busy, so it may take a week to get a hold of me. If I don’t respond to the email, private message me here.

  • Avatar John Min says:

    Dr. Yoho, I would love to get your take on Medicine Girl’s posts…she is bringing up some information that I would like someone smarter than me to critique…such as Vitamin D as sold as a supplement is the main ingredient in rat poison. I checked, it seems to be true. Of course the dose matters but synthetic D may be terrible for the body, getting too much calcium. She pretty much trashed all or most supplements and stated that ‘purified’ molecules, eg, ascorbic acid is not good for us, nor are the B vitamin supplements. She makes a lot of sense, I was wondering if you noticed any errors in her logic? Your opinion means a lot to me.

    https://medicinegirl.substack.com/p/turning-your-organs-to-stone-the

    • Avatar Randy says:

      I wonder which mega-drug company she works for. Big Pharma is forever putting out scientific-sounding propaganda disparaging inexpensive supplements.

      • Avatar Robert Yoho, MD says:

        That’s what I’ve heard.

      • Avatar John Min says:

        You are right about Big pharma putting out flawed studies to show vitamins and supplements don’t work but I DO NOT think she works for any industry. Consider that supplement makers are often subsidiary companies of big Pharma / big Agra – everybody wants a piece of the huge supplement consumer pie. She does like the work of that Substack Agent, and frequently quotes or links to the Agent’s posts which gives me pause. Dr. Yoho has recently shown the Agent’s work to be suspect and his article on dinosaurs to be completely flawed. Abiotic oil however, seems right, seeing as how Titan, Saturn’s largest moon, is rich with hydrocarbons without biology to make it happen. So hard to get past marketing / psyops to know what is real and good, so hard to know who to trust. I do trust Dr. Yoho…anyone who owns their mistakes as soon as they know is someone interested in what is true, not in protecting a product, brand or ego.

    • Avatar Robert Yoho, MD says:

      From what I understand, she is in the same category as that Agent Substack. That said, I haven’t looked at it.

  • Avatar Denigee says:

    what do you know about wild yam cream for post menopauseal women?

  • Avatar Randy says:

    Milk basic protein (MBP) is a fraction of whey protein that promotes bone formation and suppresses bone resorption. The biological mechanism involves stimulating osteoblast proliferation for bone growth while inhibiting osteoclast activity, which reduces the breakdown of bone tissue. This dual action helps maintain a positive bone remodeling balance, leading to increased bone strength and reduced markers of bone loss, particularly in the lower extremities and spine. Clinical studies indicate that daily supplementation of 40 mg significantly increases bone mineral density (BMD) and improves bone metabolism in menopausal and elderly women. u2014 Clipped from a Brave AI summary of MBP.

    Supp. available from Amazon, among others: https://a.co/d/067dlrRc

    Clinical trial: https://pubmed.ncbi.nlm.nih.gov/16133638/

  • Avatar Susan Davis says:

    The Marodyne Liv machine costs over $1,000. Can you suggest the cheaper vibrating exercise machines on Amazon? Does it have to be the Marodyne Liv expensive one?

  • Avatar BRobi says:

    Dr. Yoho….Gosh, I love reading your stuff. Thanks for the time you spend on the depth and breadth of each subject. It’s rather astonishing.

    I was recently advised to start Metagenics Bone Builder Plus, which contains “Calcium as microcrystalline hydroxyapatite concentrate (MCHC), a crystalline form that naturally contains calcium along with minerals such as phosphorus and trace minerals found in bone and is described as highly absorbable.” Specifically: Vitamin D (as cholecalciferol) 50 mcg 250%

    Calcium (as MCHC) 420mg 32%

    Phosphorus (as MCHC) 160 mg 13%

    Microcrystalline Hydroxyapatite Concentrate (MCHC) 1.9 g I knew enough not to supplement with the other forms that have been pushed on us for years…but I thought this might be ok….But reading this stack, I’m thinking it might still make it to the Yoho Naughty List? (I supplement with Vit D above and beyond this measly amt, and what I hope is a bone-preserving lifestyle….)

    I’m particularly interested as I recommended it to a friend that’s being treated with estrogen blockers for her ER+ BC 🙁 I certainly do not wish to do her any harm.

    THANKS

  • Avatar Leslie Johnson says:

    My mother had her jaw destroyed by these meds and I know someone who broke both femurs tripping in the laundry room. Just common sense is needed, what builds bones? I am taking mag glycinate now, it’s concerning how many symptoms come from a deficiency there.

  • Avatar Christine says:

    Can you please tell me what source of boron to take? The safest one?

  • Avatar BlazeBey says:

    Dr. Yoho, I watched a very short video yesterday on Telegram of a man with severe Parkinson take ONE drop of cannabis oil and he had so much calm and relief, ONE DROP. They also posted a link to Rick Simpsonu2019s u2018how tou2019 on making your own oil. Thank you for all you do and share; many Blissings! uD83EuDE77uD83EuDD0DuD83EuDE77

    The title of the vid on YouTube is: u2018The Immediate Effects of RSO on Parkinson’s Diseasu2019.

    This is the how to vid title (canu2019t post links here): How to Make Full Extract Cannabis Oil (RSO) with Rick Simpson!

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